Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia

被引：30
|
作者：
Wilkinson, ID
Hadjivassiliou, M
Dickson, JM
Wallis, L
Grünewald, RA
Coley, SC
Widjaja, E
Griffiths, PD
机构：
[1] Univ Sheffield, Acad Unit Radiol, Sheffield, S Yorkshire, England
[2] Sheffield Teaching Hosp NHS Fdn Trust, Royal Hallamshire Hosp, Dept Neurol, Sheffield, S Yorkshire, England
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2005年 / 76卷 / 07期
关键词：
D O I：
10.1136/jnnp.2004.049809
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Gluten sensitivity can manifest with ataxia. The metabolic status of the cerebellum was investigated in 15 patients with gluten ataxia and 10 controls using proton MR spectroscopy. Significant differences were present in mean N-acetyl aspartate levels at short echo time and N-acetyl aspartate/choline ratios at long echo time between the patient and control groups. These data support the hypothesis that cerebellar neuronal physiology differs between patients with gluten ataxia and healthy controls.
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页码：1011 / 1013
页数：3
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