Increasing the frequency of cropping in dryland systems in the northern Great Plains requires the application of N fertilizer to maintain optimum crop yields. A 12-yr annual cropping rotation [spring wheat (Triticum aestivum L.)-winter wheat-sunflower (Helianthus annuus L.)] under dryland conditions was monitored to determine the influence of tillage system [conventional till (CT), minimum till (MT), and no till (NT)I and N Fertilizer rate (34, 67, and 101 kg N ha(-1)) on N removed in grain and annual changes in postharvest soil NO3-N. Nitrogen removal in the grain increased with increasing N rate in most years. Total grain N removal was lowest with NT at the lowest N rate and highest with NT st the highest N rate compared with CT, Total grain N removal after 12 cropping seasons was 144, 84, and 61% of the total N applied for the 34, 67, and 101 kg N ha(-1) fertilizer rates, respectively. Residual soil NO3-N levels were not affected by N rate or tillage system in the first 3 yr, but they increased significantly following consecutive drought years, Residual NO3-N in the 150-cm soil profile tended to be higher with CT and MT than with NT, Soil NO3-N movement below the crop root zone may have occurred in 1 or 2 yr when precipitation was above average, Results indicate that NT, with annual cropping, may reduce the quantity of residual soil NO3-N available for leaching compared with MT and CT systems.