Derivatisation for separation and detection in capillary electrophoresis (2015-2017)

被引:21
|
作者
Wuethrich, Alain [1 ]
Quirino, Joselito P. [2 ]
机构
[1] Univ Queensland, AIBN, Ctr Personalised Nanomed, Brisbane, Qld, Australia
[2] Univ Tasmania, Australian Ctr Res Separat Sci ACROSS, Sch Phys Sci Chem, Hobart, Tas, Australia
基金
瑞士国家科学基金会;
关键词
Analyte modification; Capillary electrophoresis; Derivatisation; Sensitivity enhancement; Sequential injection; Stacking; LASER-INDUCED FLUORESCENCE; AMINO-ACIDS; ELECTROKINETIC CHROMATOGRAPHY; MASS-SPECTROMETRY; ELECTROMIGRATION METHODS; NUTRITIONAL SUPPLEMENTS; LIQUID-CHROMATOGRAPHY; HUMAN PLASMA; UV-DETECTION; LIF METHOD;
D O I
10.1002/elps.201700252
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Derivatisation is an integrated part of many analytical workflows to enable separation and detection of the analytes. In CE, derivatisation is adapted in the four modes of pre-capillary, in-line, in-capillary, and post-capillary derivatisation. In this review, we discuss the progress in derivatisation from February 2015 to May 2017 from multiple points of view including sections about the derivatisation modes, derivatisation to improve the analyte separation and analyte detection. The advancements in derivatisation procedures, novel reagents, and applications are covered. A table summarising the 46 reviewed articles with information about analyte, sample, derivatisation route, CE method and method sensitivity is provided.
引用
收藏
页码:82 / 96
页数:15
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