An efficient and facile one-pot synthesis of cyanohydrin esters from carbonyl compounds catalyzed by iron(III) chloride

被引:40
|
作者
Iwanami, K [1 ]
Aoyagi, M [1 ]
Oriyama, T [1 ]
机构
[1] Ibaraki Univ, Fac Sci, Mito, Ibaraki 3108512, Japan
关键词
cyanation; cyanohydrin ester; trimethylsilyl cyanide; acid anhydride; carbonyl compound; iron(III) chloride;
D O I
10.1016/j.tetlet.2005.09.003
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A variety of cyanohydrin esters were readily prepared from carbonyl compounds with trimethylsilyl cyanide and acid anhydride under the influence of a catalytic amount of iron(III) chloride in a convenient one-pot procedure. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7487 / 7490
页数:4
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