The molecular genetics of laryngeal cancer

被引：24

作者：

Loyo, Myriam ^{[1
]}

Pai, Sara I. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Baltimore, MD 21287 USA

来源：

OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA | 2008年 / 41卷 / 04期

关键词：

D O I：

10.1016/j.otc.2008.01.019

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The authors present the clinical relevance of molecular genetics to laryngeal cancer in terms of helping to develop novel diagnostic, prognostic, and therapeutic strategies. They discuss how molecular diagnostics can detect abnormalities in lesions not yet appreciated histologically, and thus detect early recurrences. Patient management with novel targeted therapies for head and neck squamous cell carcinoma in the clinical arena is presented, with treatment options tailored to the individual patient and his or her cancer among them, with the goal of improving clinical outcomes.

引用

页码：657 / +

页数：17

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