Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti-Inflammatory Activities

被引：5
|
作者：
Dong, Hongjing [1 ]
Geng, Yanling [1 ]
Wang, Xueyong [2 ]
Song, Xiangyun [1 ]
Wang, Xiao [1 ]
Yu, Jinqian [1 ]
机构：
[1] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Shandong Key Lab TCM Qual Control Technol, Jinan 250014, Shandong, Peoples R China
[2] Beijing Univ Chinese Med, Coll Chinese Mareria Med, Beijing 100102, Peoples R China
来源：
MOLECULES | 2018年 / 23卷 / 10期
关键词：
Scindapsus officinalis; monoterpene glycoside; phenyl glycoside; caffeoyl derivative; anti-inflammatory activity;
D O I：
10.3390/molecules23102577
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4-7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds 3 and 7 exhibited moderate inhibitory effects on NO production with IC50 values of 12.2 +/- 0.8 and 18.9 +/- 0.3 mu M, respectively.
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页数：10
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