The Role of Vitamin D in Diabetic Nephropathy: A Translational Approach

被引：17

作者：

Delrue, Charlotte ^{[1
]}

Speeckaert, Reinhart ^{[2
]}

Delanghe, Joris R. ^{[3
]}

Speeckaert, Marijn M. ^{[1
,4
]}

机构：

[1] Ghent Univ Hosp, Dept Nephrol, B-9000 Ghent, Belgium

[2] Ghent Univ Hosp, Dept Dermatol, B-9000 Ghent, Belgium

[3] Univ Ghent, Dept Diagnost Sci, B-9000 Ghent, Belgium

[4] Res Fdn Flanders FWO, B-1000 Brussels, Belgium

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2022年 / 23卷 / 02期

关键词：

diabetes mellitus; diabetic nephropathy; vitamin D; D-RECEPTOR GENE; SERUM 25-HYDROXYVITAMIN D; D-BINDING PROTEIN; D DEFICIENCY; KIDNEY-DISEASE; MICROVASCULAR COMPLICATIONS; PODOCYTE INJURY; D ANALOG; 1,25-DIHYDROXYVITAMIN D-3; ENDOTHELIAL FUNCTION;

D O I：

10.3390/ijms23020807

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

According to several animal and human studies, vitamin D appears to play a significant role in the development of diabetic nephropathy. However, the possible renoprotective effect of vitamin D and its influence on the reversal of already existing renal damage remains doubtful. At this moment, there are a few hypotheses concerning the underlying molecular and genetic mechanisms including the link between vitamin D and inflammation, oxidative stress, and extracellular matrix accumulation. The present review aims to investigate the potential role of vitamin D in the development of diabetic kidney disease from a translational approach.

引用

页数：17

共 50 条

[21] Losartan and vitamin D analog synergistically prevent diabetic nephropathy in mice
不详
Nature Clinical Practice Nephrology, 2009, 5 (1): : 3 - 3
[22] Vitamin D and diabetic nephropathy: a systematic review and meta-analysis
Derakhshanian, Hoda
Djafarian, Kurosh
Shab-Bidar, Sakineh
Speakman, John
Nadimi, Hoda
ANNALS OF NUTRITION AND METABOLISM, 2015, 67 : 451 - 452
[23] Effect of Vitamin D on Urinary Angiotensinogen Level in Early Diabetic Nephropathy
Mahapatra, Himansu Sekhar
Kumar, Adarsh
Kulshreshtha, Bindu
Chitkara, Anubhuti
Kumari, Anamika
INDIAN JOURNAL OF NEPHROLOGY, 2021, 31 (04) : 341 - 348
[24] Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats
Tian, Yanyan
Lv, Guodong
Yang, Ye
Zhang, Yuanyuan
Yu, Rui
Zhu, Jia
Xiao, Lati
Zhu, Jun
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 7 (06): : 3028 - 3037
[25] EFFECT OF VITAMIN D ON URINARY ANGIOTENSIOGEN LEVEL IN EARLY DIABETIC NEPHROPATHY
Mahapatra, Himansu
Kumar, Adarsh
Kulshreshtha, Bindu
Chirkara, Anubhuti
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2020, 35 : 1324 - 1324
[26] Haplotypes in vitamin D receptor gene encode risk in diabetic nephropathy
Razi, Farideh
Meshkani, Marzieh Arshadi
Zarrabi, Fariba
Sadr, Maryam
Asgarbeik, Saeedeh
Bandarian, Fatemeh
Forouzanfar, Katayoon
Amoli, Mahsa Mohammad
GENE, 2019, 683 : 149 - 152
[27] Vitamin D and diabetic nephropathy: A systematic review and meta-analysis
Derakhshanian, Hoda
Shab-Bidar, Sakineh
Speakman, John R.
Nadimi, Hoda
Djafarian, Kurosh
NUTRITION, 2015, 31 (10) : 1189 - 1194
[28] Vitamin D deficiency and related risk factors in patients with diabetic nephropathy
Xiao, Xiaoyan
Wang, Yajuan
Hou, Yanlian
Han, Feng
Ren, Jianmin
Hu, Zhao
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2016, 44 (03) : 673 - 684
[29] Study of Association of Vitamin D Receptor Gene Polymorphisms with Diabetic Nephropathy
Esha, Bhuiya
Yogaprabhu, Saravanan
Sneha, Janaki
Vijayalakshmi, Karthick
Mohan, Viswanathan
Radha, Venkatesan
Bodhini, Dhanasekaran
JOURNAL OF DIABETOLOGY, 2024, 15 (02) : 222 - 228
[30] Vitamin D Receptor Signaling in Podocytes Protects against Diabetic Nephropathy
Wang, Youli
Deb, Dilip K.
Zhang, Zhongyi
Sun, Tao
Liu, Weicheng
Yoon, Dosuk
Kong, Juan
Chen, Yunzi
Chang, Anthony
Li, Yan Chun
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2012, 23 (12): : 1977 - 1986

← 1 2 3 4 5 →