T-cell costimulation

被引:0
|
作者
Hutloff, A. [1 ]
机构
[1] Deutsch Rheuma Forschungszentrum Berlin DRFZ, D-10117 Berlin, Germany
来源
ZEITSCHRIFT FUR RHEUMATOLOGIE | 2011年 / 70卷 / 07期
关键词
T-lymphocytes; Autoimmunity; CD28; TIGIT; VISTA; CD226;
D O I
10.1007/s00393-011-0862-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent publications regarding the function of the T-cell costimulators CD226 and TIGIT as well as the identification of the new costimulatory ligand VISTA are of great interest for an understanding of autoimmune diseases. Both systems display striking similarities to the well-established costimulators CD28/CTLA-4 and PD-1.
引用
收藏
页码:588 / 591
页数:4
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