Mucosal associated invariant T cells and the immune response to infection

被引:17
|
作者
Gold, Marielle C. [1 ,2 ]
Lewinsohn, David M. [1 ,2 ]
机构
[1] Oregon Hlth & Sci Univ, Portland, OR 97239 USA
[2] Portland VA Med Ctr, Portland, OR 97239 USA
关键词
Mucosal associated invariant T (MAIT) cells; iNKT cells; MR1; MHC-I; Mucosal immunity; Mycobacterium tuberculosis; MR1 ANTIGEN PRESENTATION; MAIT CELLS; CRYSTAL-STRUCTURE; ALPHA-CHAIN; GENES; TCR; RECOGNITION; EXPRESSION; MOLECULES; SYMBIOSIS;
D O I
10.1016/j.micinf.2011.03.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Mucosal associated invariant T cells are unique T cells localized at high frequencies at the portals of entry for many pathogens. Mucosal associated invariant T cells display a variety of characteristics that suggest their function is to act as effectors in the initial control of microbial infection at mucosal sites. Published by Elsevier Masson SAS on behalf of Institut Pasteur.
引用
收藏
页码:742 / 748
页数:7
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