Antioxidant, Anti-Inflammatory, and Immunomodulatory Properties of Tea-The Positive Impact of Tea Consumption on Patients with Autoimmune Diabetes

被引:24
|
作者
Winiarska-Mieczan, Anna [1 ]
Tomaszewska, Ewa [2 ]
Jachimowicz, Karolina [1 ]
机构
[1] Univ Life Sci Lublin, Inst Anim Nutr & Bromatol, Akad St 13, PL-20950 Lublin, Poland
[2] Univ Life Sci Lublin, Fac Vet Med, Dept Anim Physiol, Akad St 12, PL-20950 Lublin, Poland
关键词
autoimmune diabetes; tea; polyphenols; antioxidant; anti-inflammatory; immunomodulatory; INDUCED OXIDATIVE STRESS; NF-KAPPA-B; GREEN TEA; TNF-ALPHA; NITRIC-OXIDE; GLUCOSE-METABOLISM; CAMELLIA-SINENSIS; ENZYME-ACTIVITIES; ADULTS LADA; MOUSE MODEL;
D O I
10.3390/nu13113972
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The physiological markers of autoimmune diabetes include functional disorders of the antioxidative system as well as progressing inflammation and the presence of autoantibodies. Even though people with type 1 diabetes show genetic predispositions facilitating the onset of the disease, it is believed that dietary factors can stimulate the initiation and progression of the disease. This paper analyses the possibility of using tea as an element of diet therapy in the treatment of type 1 diabetes. Based on information available in literature covering the last 10 years, the impact of regular tea consumption or diet supplements containing tea polyphenols on the oxidative status as well as inflammatory and autoimmune response of the organism was analyzed. Studies conducted on laboratory animals, human patients, and in vitro revealed positive effects of the consumption of tea or polyphenols isolated therefrom on the diabetic body. Few reports available in the literature pertain to the impact of tea on organisms affected by type 1 diabetes as most (over 85%) have focused on cases of type 2 diabetes. It has been concluded that by introducing tea into the diet, it is possible to alleviate some of the consequences of oxidative stress and inflammation, thus limiting their destructive impact on the patients' organisms, consequently improving their quality of life, regardless of the type of diabetes. Furthermore, elimination of inflammation should reduce the incidence of immune response. One should consider more widespread promotion of tea consumption by individuals genetically predisposed to diabetes, especially considering the drink's low price, easy availability, overall benefits to human health, and above all, the fact that it can be safely used over extended periods of time, regardless of the patient's age.
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页数:25
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