A distinctive type of widespread congenital melanocytic nevus with large nodules

被引:12
|
作者
Rose, C
Kaddu, S
El-Sherif, TF
Kerl, H
机构
[1] Graz Univ, Dept Dermatol, A-8036 Graz, Austria
[2] Univ Wurzburg, Dept Dermatol, D-8700 Wurzburg, Germany
[3] Hosp Gen Reference Natl, NDjamena, Chad
关键词
D O I
10.1067/S0190-9622(03)00365-7
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report an unusual case of congenital melanocytic nevus presenting in a 19-year-old African woman as widespread papules and variably sized nodules and tumors affecting the entire body, including the palms, soles, and oral mucous membrane. Histopathologic examination of 3 representative skin lesions showed mainly dermal aggregations of round to oval, focally pigmented, monomorphous melanocytes, arranged in nodular and plexiform patterns. Scattered areas with spindle-shaped dendritic melanocytes surrounded by fibrosis were also noted in the center of the lesions. The clinical and histopathologic findings were similar to those in 2 other previously reported cases, except that in 1 of the earlier cases the skin nodules were composed of spindle-shaped cells, suggesting a type of blue nevus. The findings in our case indicate a broader spectrum of morphologic features in this condition, with dermal aggregations of melanocytes showing congenital features, representing a common histopathologic denominator. Based oil this observation, we suggest the term "widespread congenital dermal nevus with large nodules" to he the most appropriate for this rare, but distinctive, type of congenital nevus.
引用
收藏
页码:732 / 735
页数:4
相关论文
共 50 条
  • [21] Melanoma in a congenital melanocytic nevus
    Zeglinski-Spinney, Amy
    Kirchhof, Mark G.
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2024, 196 (18) : E625 - E625
  • [22] Congenital melanocytic Giant Nevus
    Thayssen, Maike
    Wolf, Monika
    Hoeger, Peter
    Singer, Dominique
    ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, 2017, 221 (02): : 92 - 93
  • [23] ACRAL CONGENITAL MELANOCYTIC NEVUS
    REILLY, G
    SARUK, M
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 1983, 22 (01) : 62 - 63
  • [24] Congenital Melanocytic Nevus with Distinctive Nevus Cell Proliferation within Multiple Epidermal Cyst-Like Changes
    Joo, Hong Jin
    Kim, Jung Eun
    Kang, Hoon
    ANNALS OF DERMATOLOGY, 2016, 28 (01) : 123 - 124
  • [25] Benign melanocytic lymph node deposits in the setting of giant congenital melanocytic nevi: the large congenital nodal nevus
    Bowen, Anneli R.
    Duffy, Keith L.
    Clayton, Frederic C.
    Andtbacka, Robert H. I.
    Florell, Scott R.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2015, 42 (11) : 832 - 839
  • [26] Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib
    Berna, R.
    Hasbun, T.
    Adams, D.
    Moon, A. T.
    Treat, J. R.
    PEDIATRIC DERMATOLOGY, 2024, 41 (05) : 936 - 937
  • [27] Proliferative nodules in a giant congenital melanocytic nevus-case report and review of the literature
    van Houten, Annemarie H.
    van Dijk, Marcory C. R. F.
    Schuttelaar, Marie-Louise A.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2010, 37 (07) : 764 - 776
  • [28] PLEXIFORM SPINDLE CELL NEVUS - A DISTINCTIVE VARIANT OF PLEXIFORM MELANOCYTIC NEVUS
    BARNHILL, RL
    MIHM, MC
    MAGRO, CM
    HISTOPATHOLOGY, 1991, 18 (03) : 243 - 247
  • [29] Treatment of a Giant Congenital Melanocytic Nevus in the Adult Review of the Current Management of Giant Congenital Melanocytic Nevus
    Su, Jeannie J.
    Chang, Daniel K.
    Mailey, Brian
    Gosman, Amanda
    ANNALS OF PLASTIC SURGERY, 2015, 74 : S57 - S61
  • [30] Large congenital melanocytic nevus with metastatic melanoma with a probable primary in the lung
    Rao, G. Raghurama
    Prasad, B. K. Durga
    Amareswar, A.
    Vijaya, K. T.
    Sujatha
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2011, 77 (01): : 51 - 54