Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

被引：0
|
作者：
Anderson, Nick R. [1 ]
Li, Hui [2 ]
Harris, Mason W. [1 ]
Qiu, Shaowei [1 ]
Paterson, Andrew J. [3 ]
Bhatia, Ravi [4 ]
机构：
[1] Univ Alabama Birmingham, Div Hematol & Oncol, Birmingham, AL USA
[2] Univ Alabama Birmingham, Div Hematol Oncol, Birmingham, AL 35294 USA
[3] Univ Alabama Birmingham, Div Endocrinol Diabet & Metab, Birmingham, AL USA
[4] Univ Alabama Birmingham, Dept Med, Div Hematol & Oncol, Birmingham, AL 35294 USA
来源：
BLOOD | 2019年 / 134卷
关键词：
D O I：
10.1182/blood-2019-124379
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
909
引用
收藏
页数：3
相关论文
共 50 条
  • [41] FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia
    Kim, Hyung-Gyoon
    Kojima, Kyoko
    Swindle, C. Scott
    Cotta, Claudiu V.
    Huo, Yongliang
    Reddy, Vishnu
    Klug, Christopher A.
    BLOOD, 2008, 111 (03) : 1567 - 1574
  • [42] Measurable Residual FLT3-ITD before Allogeneic Transplant for Acute Myeloid Leukemia
    Dillon, Laura W.
    Gui, Gege
    Ravindra, Niveditha
    Andrew, Georgia
    Mukherjee, Devdeep
    Wong, Zoe
    Huang, Ying
    Gerhold, Jason
    Holman, Matthew
    Miller, Jeffrey E.
    Auletta, Jeffery J.
    El Chaer, Firas
    Devine, Steven M.
    Jimenez, Antonio M. Jimenez
    de Lima, Marcos
    Litzow, Mark R.
    Kebriaei, Partow
    Saber, Wael
    Spellman, Stephen R.
    Page, Kristin M.
    Hourigan, Christopher S.
    BLOOD, 2023, 142
  • [43] Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse
    Garg, Manoj
    Nagata, Yasunobu
    Kanojia, Deepika
    Mayakonda, Anand
    Yoshida, Kenichi
    Keloth, Sreya Haridas
    Zang, Zhi Jiang
    Okuno, Yusuke
    Shiraishi, Yuichi
    Chiba, Kenichi
    Tanaka, Hiroko
    Miyano, Satoru
    Ding, Ling-Wen
    Alpermann, Tamara
    Sun, Qiao-Yang
    Lin, De-Chen
    Chien, Wenwen
    Madan, Vikas
    Liu, Li-Zhen
    Tan, Kar-Tong
    Sampath, Abhishek
    Venkatesan, Subhashree
    Inokuchi, Koiti
    Wakita, Satoshi
    Yamaguchi, Hiroki
    Chng, Wee Joo
    Kham, Shirley-Kow Yin
    Yeoh, Allen Eng-Juh
    Sanada, Masashi
    Schiller, Joanna
    Kreuzer, Karl-Anton
    Kornblau, Steven M.
    Kantarjian, Hagop M.
    Haferlach, Torsten
    Lill, Michael
    Kuo, Ming-Chung
    Shih, Lee-Yung
    Blau, Igor-Wolfgang
    Blau, Olga
    Yang, Henry
    Ogawa, Seishi
    Koeffler, H. Phillip
    BLOOD, 2015, 126 (22) : 2491 - 2501
  • [44] The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia
    Li, Xia
    Yin, Xiufeng
    Wang, Huafeng
    Huang, Jiansong
    Yu, Mengxia
    Ma, Zhixin
    Li, Chenying
    Zhou, Yile
    Yan, Xiao
    Huang, ShuJuan
    Jin, Jie
    ONCOTARGET, 2017, 8 (08) : 12764 - 12774
  • [45] The Combination Effect of Homoharringtonine and Ibrutinib on FLT3-ITD Mutant Acute Myeloid Leukemia
    Li, Xia
    Yin, Xiufeng
    Wang, Huafeng
    Huang, Jiansong
    Yu, Mengxia
    Ma, Zhixin
    Li, Chenying
    Zhou, Yile
    Yan, Xiao
    Huang, Shujuan
    Jin, Jie
    BLOOD, 2016, 128 (22)
  • [46] Prognostic Impact of Subclinical FLT3-ITD Microclones in Patients with Acute Myeloid Leukemia
    Olson, Paul
    Gabdoulline, Razif
    Shahswar, Rabia
    Kloos, Arnold
    Venturini, Letizia
    Arnhardt, Isabell
    Hupe, Henri C.
    Panagiota, Victoria
    Stadler, Michael
    Eder, Matthias
    Beutel, Gernot
    Dammann, Elke
    Poll, Piroska
    Bergmann, Anke
    Didonato, Nataliya
    Heidel, Florian H.
    Thol, Felicitas R.
    Heuser, Michael
    BLOOD, 2024, 144 : 847 - 848
  • [47] The Effect of Sorafenib Therapy on the Outcome of Acute Myeloid Leukemia with FLT3-ITD Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
    Xuan, Li
    Wang, Yu
    Huang, Fen
    Wu, Bingyi
    Fan, Zhiping
    Xu, Na
    Ye, Jieyu
    Sun, Jing
    Huang, Xiaojun
    Liu, Qifa
    BLOOD, 2017, 130
  • [48] Impact of FLT3-ITD Mutations in Patients with Normal Karyotype Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation
    Grillo, Giovanni
    Zucchetti, Elisa
    Inzoli, Elena
    Mancini, Valentina
    Forno, Barbara
    Lotesoriere, Ivana
    Bertani, Giambattista
    Cairoli, Roberto
    BLOOD, 2017, 130
  • [49] Effect of Sorafenib on the Outcomes of Patients With FLT3-ITD Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
    Xuan, Li
    Wang, Yu
    Huang, Fen
    Jiang, Erlie
    Deng, Lan
    Wu, Bingyi
    Fan, Zhiping
    Liang, Xinquan
    Xu, Na
    Ye, Jieyu
    Lin, Ren
    Yin, Changxin
    Zhang, Yuanyuan
    Sun, Jing
    Han, Mingzhe
    Huang, Xiaojun
    Liu, Qifa
    CANCER, 2018, 124 (09) : 1954 - 1963
  • [50] Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation
    Ortlepp, Claudia
    Steudel, Christine
    Heiderich, Caroline
    Koch, Sina
    Jacobi, Angela
    Ryser, Martin
    Brenner, Sebastian
    Bornhaeuser, Martin
    Brors, Benedikt
    Hofmann, Wolf-Karsten
    Ehninger, Gerhard
    Thiede, Christian
    EXPERIMENTAL HEMATOLOGY, 2013, 41 (05) : 444 - 461
12345