Clinical management of a granulomatous tubulointerstitial nephritis associated with a bilateral granulomatous anterior uveitis: A challenging case report and review of the literature

被引：2

作者：

Taghavi, Maxime ^{[1
,3
]}

Mesquita, Maria ^{[1
]}

David, Cristina ^{[1
]}

Geers, Caroline ^{[2
]}

Pozdzik, Agnieszka ^{[1
]}

Nortier, Joelle ^{[1
]}

机构：

[1] Univ Libre Bruxelles, Brugmann Univ Hosp, Dept Nephrol & Dialysis, Brussels, Belgium

[2] Univ Libre Bruxelles, Brugmann Univ Hosp, Dept Pathol, Brussels, Belgium

[3] Univ Libre Bruxelles, Univ Hosp Brugmann, Dept Nephrol & Dialysis, Pl A Gehuchten 4, B-1020 Brussels, Belgium

来源：

CLINICAL NEPHROLOGY | 2022年 / 98卷 / 03期

关键词：

interstitial nephritis; granuloma; sarcoidosis; TINU; syndrome; uveitis; INTERSTITIAL NEPHRITIS; SARCOIDOSIS; ENDOPHTHALMITIS; PYELONEPHRITIS; DIAGNOSIS; DISEASE;

D O I：

10.5414/CN110841

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Acute granulomatous tubulo-interstitial nephritis (GTIN) is a rare finding in renal biopsy. Differential diagnosis is facili-tated when GTIN is associated with granu-lomatous bilateral anterior uveitis (GBAU). Nevertheless, differentiation between a rare form of granulomatous tubulointerstitial nephritis and uveitis syndrome (TINU) and sarcoidosis can be challenging. We report a case of biopsy-proven GTIN with concomi-tant GBAU, leading to a dead-end diagnosis. We discuss workup and propose a diagnostic algorithm based on a literature review. We also report a successful treatment of oph-thalmologic and renal relapse using myco-phenolate mofetil.

引用

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页码：155 / 161

页数：7

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