Syntheses of optically active, unusual, and biologically important hydroxy-amino acids from D-glucosamine

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作者
Shinozaki, K
Mizuno, K
Masaki, Y
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O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Manipulation of D-glucosamine as a chiral pool including stereoinversion of the C3-hydroxyl group, degradation of the C6-carbon, and/or one carbon homologation at the C1-position realized chiral syntheses of (2S,3S)-dihydroxy-(4S)-amino acid moieties, important structural components of a gastroprotective substance AI-77-B and a group of antitumor substances calyculins.
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页码:11 / 14
页数:4
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