Serotonergic Psychedelics in Neural Plasticity

被引：16
|
作者：
Lukasiewicz, Kacper [1 ]
Baker, Jacob J. [1 ]
Zuo, Yi [1 ]
Lu, Ju [1 ]
机构：
[1] Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, Santa Cruz, CA 95064 USA
来源：
FRONTIERS IN MOLECULAR NEUROSCIENCE | 2021年 / 14卷
关键词：
psychedelics; synapse; neural plasticity; 5-HT2A; psychoplastogen; psychiatric disorders; SYNAPTIC PLASTICITY; PREFRONTAL CORTEX; STRUCTURAL PLASTICITY; CLASSIC HALLUCINOGENS; PURKINJE-CELLS; RECEPTOR; KETAMINE; IBOGAINE; PSILOCYBIN; DYNAMICS;
D O I：
10.3389/fnmol.2021.748359
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Psychedelics, compounds that can induce dramatic changes in conscious experience, have been used by humans for centuries. Recent studies have shown that certain psychedelics can induce neural plasticity by promoting neurite growth and synapse formation. In this review, we focus on the role of classical serotonergic psychedelics in neural plasticity and discuss its implication for their therapeutic potentials.
引用
收藏
页数：7
相关论文
共 50 条
  • [21] Serotonergic Psychedelics: A Comparative Review of Efficacy, Safety, Pharmacokinetics, and Binding Profile
    Holze, Friederike
    Singh, Nirmal
    Liechti, Matthias E.
    D'Souza, Deepak Cyril
    [J]. BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, 2024, 9 (05) : 472 - 489
  • [22] Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics
    Schindler, Emmanuelle A. D.
    Wallace, Ryan M.
    Sloshower, Jordan A.
    D'Souza, Deepak C.
    [J]. FRONTIERS IN PHARMACOLOGY, 2018, 9
  • [23] How do serotonergic psychedelics treat depression: The potential role of neuroplasticity
    Artin, Hewa
    Zisook, Sidney
    Ramanathan, Dhakshin
    [J]. WORLD JOURNAL OF PSYCHIATRY, 2021, 11 (06):
  • [24] DEVELOPMENTAL-CHANGES IN THE BRAIN-STEM SEROTONERGIC NUCLEI OF TELEOST FISH AND NEURAL PLASTICITY
    EKSTROM, P
    [J]. CELLULAR AND MOLECULAR NEUROBIOLOGY, 1994, 14 (04) : 381 - 393
  • [25] Neuropsychological Functioning in Users of Serotonergic Psychedelics - A Systematic Review and Meta-Analysis
    Basedow, Lukas A.
    Riemer, Thomas G.
    Reiche, Simon
    Kreutz, Reinhold
    Majic, Tomislav
    [J]. FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [26] Effects of serotonergic psychedelics on mitochondria: Transdiagnostic implications for mitochondria-related pathologies
    Fissler, Patrick
    Vandersmissen, Anja
    Filippi, Marco
    Mavioglu, Rezan Nehir
    Scholkmann, Felix
    Karabatsiakis, Alexander
    Kraehenmann, Rainer
    [J]. JOURNAL OF PSYCHOPHARMACOLOGY, 2023, 37 (07) : 679 - 686
  • [27] Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
    Moliner, Rafael
    Girych, Mykhailo
    Brunello, Cecilia A.
    Kovaleva, Vera
    Biojone, Caroline
    Enkavi, Giray
    Antenucci, Lina
    Kot, Erik F.
    Goncharuk, Sergey A.
    Kaurinkoski, Katja
    Kuutti, Mirjami
    Fred, Senem M.
    Elsila, Lauri V.
    Sakson, Sven
    Cannarozzo, Cecilia
    Diniz, Cassiano R. A. F.
    Seiffert, Nina
    Rubiolo, Anna
    Haapaniemi, Hele
    Meshi, Elsa
    Nagaeva, Elina
    Ohman, Tiina
    Rog, Tomasz
    Kankuri, Esko
    Vilar, Marcal
    Varjosalo, Markku
    Korpi, Esa R.
    Permi, Perttu
    Mineev, Konstantin S.
    Saarma, Mart
    Vattulainen, Ilpo
    Casarotto, Plinio C.
    Castren, Eero
    [J]. NATURE NEUROSCIENCE, 2023, 26 (06) : 1032 - +
  • [28] The psychedelic afterglow phenomenon: a systematic review of subacute effects of classic serotonergic psychedelics
    Evens, Ricarda
    Schmidt, Marianna Elisa
    Majic, Tomislav
    Schmidt, Timo Torsten
    [J]. THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, 2023, 13
  • [29] Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
    Rafael Moliner
    Mykhailo Girych
    Cecilia A. Brunello
    Vera Kovaleva
    Caroline Biojone
    Giray Enkavi
    Lina Antenucci
    Erik F. Kot
    Sergey A. Goncharuk
    Katja Kaurinkoski
    Mirjami Kuutti
    Senem M. Fred
    Lauri V. Elsilä
    Sven Sakson
    Cecilia Cannarozzo
    Cassiano R. A. F. Diniz
    Nina Seiffert
    Anna Rubiolo
    Hele Haapaniemi
    Elsa Meshi
    Elina Nagaeva
    Tiina Öhman
    Tomasz Róg
    Esko Kankuri
    Marçal Vilar
    Markku Varjosalo
    Esa R. Korpi
    Perttu Permi
    Konstantin S. Mineev
    Mart Saarma
    Ilpo Vattulainen
    Plinio C. Casarotto
    Eero Castrén
    [J]. Nature Neuroscience, 2023, 26 : 1032 - 1041
  • [30] Neural effects of psychedelics: Complexity the key word
    Jones, Brett D. M.
    Husain, M. Ishrat
    [J]. NEUROPSYCHOPHARMACOLOGY, 2024, 49 (07) : 1067 - 1068
12345