Serotonergic Psychedelics in Neural Plasticity

被引:16
|
作者
Lukasiewicz, Kacper [1 ]
Baker, Jacob J. [1 ]
Zuo, Yi [1 ]
Lu, Ju [1 ]
机构
[1] Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, Santa Cruz, CA 95064 USA
来源
关键词
psychedelics; synapse; neural plasticity; 5-HT2A; psychoplastogen; psychiatric disorders; SYNAPTIC PLASTICITY; PREFRONTAL CORTEX; STRUCTURAL PLASTICITY; CLASSIC HALLUCINOGENS; PURKINJE-CELLS; RECEPTOR; KETAMINE; IBOGAINE; PSILOCYBIN; DYNAMICS;
D O I
10.3389/fnmol.2021.748359
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Psychedelics, compounds that can induce dramatic changes in conscious experience, have been used by humans for centuries. Recent studies have shown that certain psychedelics can induce neural plasticity by promoting neurite growth and synapse formation. In this review, we focus on the role of classical serotonergic psychedelics in neural plasticity and discuss its implication for their therapeutic potentials.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Psychedelics and neural plasticity
    Rachael Sumner
    Kacper Lukasiewicz
    [J]. BMC Neuroscience, 24
  • [2] Psychedelics and neural plasticity
    Sumner, Rachael
    Lukasiewicz, Kacper
    [J]. BMC NEUROSCIENCE, 2023, 24 (01)
  • [3] Psychedelics and Neural Plasticity: Therapeutic Implications
    Grieco, Steven F.
    Castren, Eero
    Knudsen, Gitte M.
    Kwan, Alex C.
    Olson, David E.
    Zuo, Yi
    Holmes, Todd C.
    Xu, Xiangmin
    [J]. JOURNAL OF NEUROSCIENCE, 2022, 42 (45): : 8439 - 8449
  • [4] Neural Geometrodynamics, Complexity, and Plasticity: A Psychedelics Perspective
    Ruffini, Giulio
    Lopez-Sola, Edmundo
    Vohryzek, Jakub
    Sanchez-Todo, Roser
    [J]. ENTROPY, 2024, 26 (01)
  • [5] Psychedelics Promote Structural and Functional Neural Plasticity
    Ly, Calvin
    Greb, Alexandra C.
    Cameron, Lindsay P.
    Wong, Jonathan M.
    Barragan, Eden, V
    Wilson, Paige C.
    Burbach, Kyle F.
    Zarandi, Sina Soltanzadeh
    Sood, Alexander
    Paddy, Michael R.
    Duim, Whitney C.
    Dennis, Megan Y.
    McAllister, A. Kimberley
    Ori-McKenney, Kassandra M.
    Gray, John A.
    Olson, David E.
    [J]. CELL REPORTS, 2018, 23 (11): : 3170 - 3182
  • [6] Serotonin toxicity of serotonergic psychedelics
    Benjamin Malcolm
    Kelan Thomas
    [J]. Psychopharmacology, 2022, 239 : 1881 - 1891
  • [7] Serotonin toxicity of serotonergic psychedelics
    Malcolm, Benjamin
    Thomas, Kelan
    [J]. PSYCHOPHARMACOLOGY, 2022, 239 (06) : 1881 - 1891
  • [8] Animal Models of Serotonergic Psychedelics
    Hanks, James B.
    Gonzalez-Maeso, Javier
    [J]. ACS CHEMICAL NEUROSCIENCE, 2013, 4 (01): : 33 - 42
  • [9] Meta-Analysis of Functional Neuroimaging Studies of the Effects of Serotonergic Psychedelics on Neural Activity
    Shepherd, Jonah H.
    Baten, Caitlin
    Klassen, Amanda M.
    Zamora, Gladys
    Saravia, Sarah
    Pritchard, Elizabeth
    Ali, Zulaikha
    Kahlon, Saneh K.
    Whitelock, Kyla
    Reyes, Fabiola A.
    Hedges, Dawson H.
    Hamilton, J. Paul
    Sacchet, Matthew D.
    Miller, Chris H.
    [J]. BIOLOGICAL PSYCHIATRY, 2023, 93 (09) : S300 - S300
  • [10] Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives
    Pallavicini, Carla
    Vilas, Martina G.
    Villarreal, Mirta
    Zamberlan, Federico
    Muthukumaraswamy, Suresh
    Nutt, David
    Carhart-Harris, Robin
    Tagliazucchi, Enzo
    [J]. NEUROIMAGE, 2019, 200 : 281 - 291