Chiral vinyl dioxazaborocines in synthesis:: Asymmetric synthesis of 5-substituted Δ2-isoxazolines via nitrile oxide cycloaddition

被引：29
|
作者：
Davies, CD
Marsden, SP [1 ]
Stokes, ESE
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
[2] Zeneca Pharmaceut, Macclesfield SK10 4TG, Cheshire, England
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 46期
基金：
英国工程与自然科学研究理事会;
关键词：
asymmetric synthesis; boron and compounds; cycloaddition; isoxazolines; nitrile oxides;
D O I：
10.1016/S0040-4039(98)01851-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Vinyl dioxazaborocines 1a-c have been subjected to 1,3-dipolar cycloadditions with benzonitrile oxide. The products are enantiomerically enriched fi-substituted Delta(2)-isoxazolines 2a-c. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8513 / 8516
页数：4
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