Cardiometabolic Features of Polycystic Ovary Syndrome: Role of Androgens

被引：32
|
作者：
Cardozo, Licy L. Yanes [1 ,2 ,4 ,5 ]
Romero, Damian G. [3 ,4 ,5 ]
Reckelhoff, Jane F. [2 ,3 ,4 ,5 ]
机构：
[1] Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA
[2] Univ Mississippi, Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA
[3] Univ Mississippi, Med Ctr, Dept Biochem, Jackson, MS 39216 USA
[4] Univ Mississippi, Med Ctr, Womens Hlth Res Ctr, Jackson, MS 39216 USA
[5] Univ Mississippi, Med Ctr, Cardio Renal Res Ctr, Jackson, MS 39216 USA
来源：
PHYSIOLOGY | 2017年 / 32卷 / 05期
基金：
美国国家卫生研究院;
关键词：
IMPAIRED GLUCOSE-TOLERANCE; CARDIOVASCULAR RISK-FACTORS; SYMPATHETIC-NERVOUS-SYSTEM; TYPE-2; DIABETES-MELLITUS; ELEVATED BLOOD-PRESSURE; INSULIN-RESISTANCE; ADIPOSE-TISSUE; OBESE WOMEN; RAT MODEL; CHRONIC HYPERINSULINEMIA;
D O I：
10.1152/physiol.00030.2016
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects reproductive-age women. Hyperandrogenemia is present in a significant fraction(similar to 80%) of women with PCOS. Increased prevalence of cardiometabolic risk factors is frequently observed in PCOS women. The present review aims to highlight the key role of androgens in mediating the negative cardiometabolic profile observed in PCOS women.
引用
收藏
页码：357 / 366
页数：10
相关论文
共 50 条
  • [1] Cardiometabolic features of polycystic ovary syndrome
    Leslie K Hoffman
    David A Ehrmann
    [J]. Nature Clinical Practice Endocrinology & Metabolism, 2008, 4 : 215 - 222
  • [2] Cardiometabolic features of polycystic ovary syndrome
    Hoffman, Leslie K.
    Ehrmann, David A.
    [J]. NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 2008, 4 (04): : 215 - 222
  • [3] POLYCYSTIC OVARY SYNDROME - ROLE OF OVARIAN ANDROGENS
    LOUVET, JP
    [J]. CONTRACEPTION FERTILITE SEXUALITE, 1984, 12 (11): : 1275 - 1279
  • [4] Androgens in Polycystic Ovary Syndrome: The Role of Exercise and Diet
    Giallauria, Francesco
    Palomba, Stefano
    Vigorito, Carlo
    Tafuri, Maria Giovanna
    Colao, Annamaria
    Lombardi, Gaetano
    Orio, Francesco
    [J]. SEMINARS IN REPRODUCTIVE MEDICINE, 2009, 27 (04) : 306 - 315
  • [5] Androgens and polycystic ovary syndrome
    Alpanes, Macarena
    Fernandez-Duran, Elena
    Escobar-Morreale, Hector F.
    [J]. EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, 2012, 7 (01) : 91 - 102
  • [6] Androgens and polycystic ovary syndrome
    Nisenblat, Vicki
    Norman, Robert J.
    [J]. CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY, 2009, 16 (03) : 224 - 231
  • [7] Polycystic ovary syndrome - Androgens and hypertension
    Reckelhoff, Jane F.
    [J]. HYPERTENSION, 2007, 49 (06) : 1220 - 1221
  • [8] AGE AND ANDROGENS IN POLYCYSTIC OVARY SYNDROME
    Chaabouni, Khansa
    Jallouli, Dana
    Khanfir, Fatma
    Makhlouf, Rihab
    Chaari, Asma
    Baccouch, Hanene
    Moalla, Chokri
    Frikha, Madiha
    Chaabene, Kais
    Elleuch, Aida
    Ayadi, Fatma
    [J]. JOURNAL OF HYPERTENSION, 2023, 41 : E99 - E99
  • [9] Cardiometabolic risk in polycystic ovary syndrome
    Studen, Katica Bajuk
    Pfeifer, Marija
    [J]. ENDOCRINE CONNECTIONS, 2018, 7 (07): : R238 - +
  • [10] Cardiometabolic Aspects of the Polycystic Ovary Syndrome
    Randeva, Harpal S.
    Tan, Bee K.
    Weickert, Martin O.
    Lois, Konstantinos
    Nestler, John E.
    Sattar, Naveed
    Lehnert, Hendrik
    [J]. ENDOCRINE REVIEWS, 2012, 33 (05) : 812 - 841
12345