Cardiometabolic risk in polycystic ovary syndrome

被引：42

作者：

Studen, Katica Bajuk ^{[1
]}

Pfeifer, Marija ^{[2
]}

机构：

[1] Univ Med Ctr Ljubljana, Nucl Med Dept, Ljubljana, Slovenia

[2] Univ Ljubljana, Fac Med, Ljubljana, Slovenia

来源：

ENDOCRINE CONNECTIONS | 2018年 / 7卷 / 07期

关键词：

PCOS; cardiovascular risk; cardiometabolic risk; hyperandrogenism; obesity; OBSTRUCTIVE SLEEP-APNEA; IMPAIRED GLUCOSE-TOLERANCE; INTIMA-MEDIA THICKNESS; CORONARY-ARTERY-DISEASE; FATTY LIVER-DISEASE; HORMONE-BINDING GLOBULIN; INSULIN-RESISTANCE; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; OBESE WOMEN;

D O I：

10.1530/EC-18-0129

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Polycystic ovary syndrome (PCOS) is a common disorder in women of reproductive age. Besides hyperandrogenism, oligomenorrhea and fertility issues, it is associated with a high prevalence of metabolic disorders and cardiovascular risk factors. Several genetic polymorphisms have been identified for possible associations with cardiometabolic derangements in PCOS. Different PCOS phenotypes differ significantly in their cardiometabolic risk, which worsens with severity of androgen excess. Due to methodological difficulties, longer time-scale data about cardiovascular morbidity and mortality in PCOS and about possible beneficial effects of different treatment interventions is missing leaving many issues regarding cardiovascular risk unresolved.

引用

页码：R238 / +

页数：14

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