Optical coherence computed tomography - art. no. 68550H

被引：0

作者：

Li, Li ^{[1
]}

Wang, Lihong V. ^{[1
]}

机构：

[1] Washington Univ, Dept Biomed Engn, Opt Imaging Lab, St Louis, MO 63117 USA

来源：

COMPLEX DYNAMICS AND FLUCTUATIONS IN BIOMEDICAL PHOTONICS V | 2008年 / 6855卷

关键词：

optical coherence tomography; diffuse optical tomography; Monte Carlo; radiative transfer;

D O I：

10.1117/12.761431

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We proposed a novel time-resolved optical tomography, optical coherence computed tomography. It married the key concepts of time-resolved diffuse optical tomography and optical coherence tomography. Both ballistic and multiple-scattered photons were measured at multiple source-detection positions by low-coherence interferometry. It measures the reemitted light with a temporal resolution of 56 femtoseconds, which is much better than the resolution of conventional time-resolved detection systems. A light-tissue interaction model was established using the time-resolved Monte Carlo method. The optical properties were then reconstructed by solving the inverse time-resolved radiative transport problem under the first Born approximation. Our initial results showed the potential of this technology to bridge the gap between diffuse optical tomography and optical coherence tomography.

引用

页码：H8550 / H8550

页数：8

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