4'-C-nucleoside derivatives: Synthesis and antiviral properties

被引：5

作者：

Alexandrova, L. A. ^{[1
]}

机构：

[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 119991, Russia

来源：

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2011年 / 37卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

hepatitis C virus; HCV NTPase/helicase; HCV RNA-dependent RNA polymerase; 4 '-C-modified nucleosides; nucleosides; nucleoside 5 '-O-triphosphates; pyrimidine nucleosides; HEPATITIS-C VIRUS; PHOSPHORAMIDATE PROTIDE TECHNOLOGY; HALO SUGAR NUCLEOSIDES; ANTI-HIV ACTIVITY; 4'-SUBSTITUTED NUCLEOSIDES; 2,3-DIDEHYDRO-2,3-DIDEOXYADENOSINE D4A; 4-SUBSTITUTED NUCLEOSIDES; POTENT INHIBITOR; REPLICATION; 4'-AZIDOCYTIDINE;

D O I：

10.1134/S1068162011060021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthesis of 4'-C-modified nucleosides and their derivatives, as well as the structure-activity relationship toward hepatitis C virus were discussed.

引用

页码：651 / 671

页数：21

共 50 条

[31] C-NUCLEOSIDE SYNTHESIS .13. SYNTHESIS OF 4'-HYDROXYMETHYLATED PYRIMIDINE RIBO-C-NUCLEOSIDES
SATO, T
NOYORI, R
TETRAHEDRON LETTERS, 1980, 21 (26) : 2535 - 2538
[32] THE SYNTHESIS OF C-NUCLEOSIDE PRECURSORS - C-ALDITOLYL POLYAZAINDENES
SHABAN, MAE
TAHA, MAM
NASR, AZ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1985, 190 (SEP): : 28 - CAB
[33] The Synthesis of a Novel C-Nucleoside Designed as Guanosine Analogue
Kourafalos, Vassilios N.
Tite, Tony
Mikros, Emmanuel
Marakos, Panagiotis
Pouli, Nicole
Balzarini, Jan
SYNLETT, 2008, (20) : 3129 - 3132
[34] SYNTHESIS OF NEW PYRIMIDINE AND PURINE C-NUCLEOSIDE ANALOGS
KHORSHIDI, HS
RODRIGEZ, AC
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 23 - CARB
[35] GLYCAL ETHERS AS STARTING MATERIALS IN C-NUCLEOSIDE SYNTHESIS
KAYE, A
REESE, CB
NEIDLE, S
NUCLEOSIDES & NUCLEOTIDES, 1988, 7 (5-6): : 609 - 612
[36] Aspects of the Chemistry of Dioxolanes: Synthesis of C-Nucleoside Analogues
Mellor, B. J.
Murray, P. E.
Thomas, E. J.
Tetrahedron, 54 (1-2):
[37] A novel approach for the synthesis of seco C-nucleoside analogues
Awad, LF
El Ashry, EH
NUCLEOSIDES & NUCLEOTIDES, 1999, 18 (4-5): : 557 - 558
[38] The synthesis of enantiomerically pure pyrazolo[4,3-c]pyridine Carbaribo C-nucleoside
Mohar, B
Kobe, J
NUCLEOSIDES & NUCLEOTIDES, 1997, 16 (7-9): : 1427 - 1429
[39] SYNTHESIS OF CERTAIN 5'-DEOXY-5'-HALO DERIVATIVES OF C-NUCLEOSIDE ANTIBIOTIC SHOWDOMYCIN
EARL, RA
TOWNSEND, LB
JOURNAL OF CARBOHYDRATES-NUCLEOSIDES-NUCLEOTIDES, 1978, 5 (04): : 305 - 315
[40] C-NUCLEOSIDE SYNTHESIS .4. SYNTHESIS OF PSEUDO-URIDINES MODIFIED AT C-5' POSITION
SATO, T
WATANABE, M
NOYORI, R
TETRAHEDRON LETTERS, 1978, (45) : 4403 - 4406

← 1 2 3 4 5 →