4'-C-nucleoside derivatives: Synthesis and antiviral properties

被引：5
|
作者：
Alexandrova, L. A. [1 ]
机构：
[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 119991, Russia
来源：
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2011年 / 37卷 / 06期
基金：
俄罗斯基础研究基金会;
关键词：
hepatitis C virus; HCV NTPase/helicase; HCV RNA-dependent RNA polymerase; 4 '-C-modified nucleosides; nucleosides; nucleoside 5 '-O-triphosphates; pyrimidine nucleosides; HEPATITIS-C VIRUS; PHOSPHORAMIDATE PROTIDE TECHNOLOGY; HALO SUGAR NUCLEOSIDES; ANTI-HIV ACTIVITY; 4'-SUBSTITUTED NUCLEOSIDES; 2,3-DIDEHYDRO-2,3-DIDEOXYADENOSINE D4A; 4-SUBSTITUTED NUCLEOSIDES; POTENT INHIBITOR; REPLICATION; 4'-AZIDOCYTIDINE;
D O I：
10.1134/S1068162011060021
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Synthesis of 4'-C-modified nucleosides and their derivatives, as well as the structure-activity relationship toward hepatitis C virus were discussed.
引用
收藏
页码：651 / 671
页数：21
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