Prevalence of Folate Deficiency in Korean Women of Reproductive Age Using a Serum Folate Assay Traceable to the WHO International Standard

被引：1

作者：

Choi, Rihwa ^{[1
,2
]}

Oh, Youngju ^{[1
]}

Park, Mi-Jung ^{[1
]}

Lee, Sang Gon ^{[1
]}

Lee, Eun Hee ^{[3
]}

机构：

[1] Green Cross Labs, Dept Lab Med, Yongin, Gyeonggi, South Korea

[2] Sungkyunkwan Univ, Dept Lab Med & Genet, Samsung Med Ctr, Sch Med, Seoul, South Korea

[3] Green Cross Labs, Yongin, Gyeonggi, South Korea

来源：

CLINICAL LABORATORY | 2021年 / 67卷 / 09期

关键词：

FOLIC-ACID; VITAMIN-B12; KNOWLEDGE;

D O I：

10.7754/Clin.Lab.2021.210144

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: We aimed to investigate serum folate level in Korean women of reproductive age and to evaluate the prevalence of folate deficiency by age using different cutoffs. Methods: We retrospectively reviewed data obtained with a serum folate assay traceable to World Health Organization international standard reference material 03/178. Results: Between September 2017 and June 2019, data from a total of 8,380 Korean women aged 15 -49 years were obtained. Mean (standard deviation) serum folate concentration for all women was 9.1 (6.7) ng/mL. Prevalence of folate deficiency using the cutoff of < 3 ng/mL was 6.2% and that for < 4 ng/mL was 14.9%. The prevalence of folate deficiency was higher in women of younger age (15 to < 25 years, even > 30% using the cutoff of 4 ng/mL) compared to other age groups. Conclusions: This study suggests that women aged 15 to < 25 years are at high risk of folate deficiency.

引用

页码：2157 / 2161

页数：5

共 25 条

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