Immunity to asexual blood stages of Plasmodium:: Is resistance to acute malaria adaptive or innate

被引：43
|
作者：
Fell, AH [1 ]
Smith, NC
机构：
[1] Stanford Univ, Human Biol Program, Stanford, CA 94305 USA
[2] Univ Technol Sydney, Dept Cell & Mol Biol, Broadway, NSW 2007, Australia
来源：
PARASITOLOGY TODAY | 1998年 / 14卷 / 09期
关键词：
D O I：
10.1016/S0169-4758(98)01298-8
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Current models of immunity to blood stages of Plasmodium invoke a primary role for T-cell dependent processes and much recent evidence implicates Th1-type responses as crucial to the control of acute malaria. But do these data stand up to close scrutiny? Here, Andy Fell and Nick Smith review recent data from rodent and human studies and suggest that Th1-type responses may not after all be important in controlling malaria infection in the blood.
引用
收藏
页码：364 / 369
页数：6
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