Patient Derived Xenograft (PDX) Models Recapitulate the Genomic-Driver Composition of Acute Leukemia Samples

被引:2
|
作者
Krivtsov, Andrei V. [1 ]
Wang, Xujun [1 ]
Farnoud, Noushin Rahnamay [1 ]
Hadler, Michael [1 ]
Martin, Marta Sanchez [2 ]
Knapp, Kristina M. [1 ]
Stein, Eytan M. [1 ]
Lipson, Doron [3 ]
Nahas, Michelle K. [3 ]
Stephens, Philip J. [3 ]
Sanford, Eric M. [3 ]
Wang, Kai [3 ]
Frampton, Garrett M. [3 ]
Brennan, Tim [3 ]
Otto, Geoff A. [3 ]
Yelensky, Roman [3 ]
Miller, Vincent [3 ]
Levine, Ross L. [1 ]
Ferrando, Adolfo A. [2 ]
Armstrong, Scott A. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Columbia Univ, New York, NY USA
[3] Fdn Med Inc, Cambridge, MA USA
关键词
D O I
10.1182/blood.V124.21.286.286
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [41] Patient-derived Xenograft (PDX) Models are Indispensable for Newly Discovered Patient Subtypes of Pancreatic Adenocarcinoma (PDAC)
    Becker, C.
    Marayati, R.
    Moffitt, R. A.
    Volmar, K. E.
    Yeh, J.
    ANNALS OF SURGICAL ONCOLOGY, 2016, 23 : S175 - S175
  • [42] Comprehensive characterization of patient-derived xenograft models of pediatric leukemia
    Rogojina, Anna
    Klesse, Laura J.
    Butler, Erin
    Kim, Jiwoong
    Zhang, He
    Xiao, Xue
    Guo, Lei
    Zhou, Qinbo
    Hartshorne, Taylor
    Garcia, Dawn
    Weldon, Korri
    Holland, Trevor
    Bandyopadhyay, Abhik
    Prado, Luz Perez
    Wang, Shidan
    Yang, Donghan M.
    Langevan, Anne-Marie
    Zou, Yi
    Grimes, Allison C.
    Assanasen, Chatchawin
    Gidvani-Diaz, Vinod
    Zheng, Siyuan
    Lai, Zhao
    Chen, Yidong
    Xie, Yang
    Tomlinson, Gail E.
    Skapek, Stephen X.
    Kurmasheva, Raushan T.
    Houghton, Peter J.
    Xu, Lin
    ISCIENCE, 2023, 26 (11)
  • [43] Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia
    Loftus, Joseph P.
    Yahiaoui, Anella
    Brown, Patrick A.
    Niswander, Lisa M.
    Bagashev, Asen
    Wang, Min
    Schauf, Allyson
    Tannheimer, Stacey
    Tasian, Sarah K.
    HAEMATOLOGICA, 2021, 106 (04) : 1067 - 1078
  • [44] ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput in vivo testing
    Gopisetty, Apurva
    Federico, Aniello
    Surdez, Didier
    Iddir, Yasmine
    Zaidi, Sakina
    Saint-Charles, Alexandra
    Waterfall, Joshua
    Saberi-Ansari, Elnaz
    Wierzbinska, Justyna
    Schlicker, Andreas
    Mack, Norman
    Schwalm, Benjamin
    Previti, Christopher
    Weiser, Lena
    Buchhalter, Ivo
    Bottcher, Anna-Lisa
    Sill, Martin
    Autry, Robert
    Estermann, Frank
    Jones, David
    Volckmann, Richard
    Zwijnenburg, Danny
    Eggert, Angelika
    Heidenreich, Olaf
    Iradier, Fatima
    Jeremias, Irmela
    Kovar, Heinrich
    Klusmann, Jan-Henning
    Debatin, Klaus-Michael
    Bomken, Simon
    Hamerlik, Petra
    Hattersley, Maureen
    Witt, Olaf
    Chesler, Louis
    Mackay, Alan
    Gojo, Johannes
    Cairo, Stefano
    Schueler, Julia
    Schulte, Johannes
    Geoerger, Birgit
    Molenaar, Jan J.
    Shields, David J.
    Caron, Hubert N.
    Vassal, Gilles
    Stancato, Louis F.
    Pfister, Stefan M.
    Jaeger, Natalie
    Koster, Jan
    Kool, Marcel
    Schleiermacher, Gudrun
    CANCER RESEARCH, 2023, 83 (07)
  • [45] Improved Patient-Derived Xenograft Model for Acute Myeloid Leukemia
    Shan, Xiaochuan
    Dos Santos, Cedric
    Zhou, Chenghui
    Ndikuyeze, Georges Habineza
    Secreto, Anthony
    Glover, Joshua
    Trotman, Winifred
    Carroll, Martin
    Danet-Desnoyers, Gwenn
    BLOOD, 2014, 124 (21)
  • [46] Genomic profiling of subcutaneous patient derived xenograft models of solid childhood cancer
    He, Funan
    Bandyopadhyay, Abhik M.
    Klesse, Laura
    Rogojina, Anna
    Butler, Erin
    Hartshorne, Taylor
    Holland, Trevor
    Prado, Luz Perez
    Langevan, Anne-Marie
    Grimes, Allison C.
    Assanasen, Chatchawin
    Lai, Zhao
    Zou, Yi
    Kurmashev, Dias
    Xu, Lin
    Xie, Yang
    Chen, Yidong
    Wang, Xiaojing
    Tomlinson, Gail E.
    Skapek, Stephen X.
    Kurmasheva, Raushan T.
    Houghton, Peter J.
    Zheng, Siyuan
    CANCER RESEARCH, 2023, 83 (07)
  • [47] Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer
    Vanessa F. Bonazzi
    Olga Kondrashova
    Deborah Smith
    Katia Nones
    Asmerom T. Sengal
    Robert Ju
    Leisl M. Packer
    Lambros T. Koufariotis
    Stephen H. Kazakoff
    Aimee L. Davidson
    Priya Ramarao-Milne
    Vanessa Lakis
    Felicity Newell
    Rebecca Rogers
    Claire Davies
    James Nicklin
    Andrea Garrett
    Naven Chetty
    Lewis Perrin
    John V. Pearson
    Ann-Marie Patch
    Nicola Waddell
    Pamela M. Pollock
    Genome Medicine, 14
  • [48] Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer
    Bonazzi, Vanessa F.
    Kondrashova, Olga
    Smith, Deborah
    Nones, Katia
    Sengal, Asmerom T.
    Ju, Robert
    Packer, Leisl M.
    Koufariotis, Lambros T.
    Kazakoff, Stephen H.
    Davidson, Aimee L.
    Ramarao-Milne, Priya
    Lakis, Vanessa
    Newell, Felicity
    Rogers, Rebecca
    Davies, Claire
    Nicklin, James
    Garrett, Andrea
    Chetty, Naven
    Perrin, Lewis
    Pearson, John, V
    Patch, Ann-Marie
    Waddell, Nicola
    Pollock, Pamela M.
    GENOME MEDICINE, 2022, 14 (01)
  • [49] Therapeutic Efficacy of CXCR4-targeted Endoradiotherapy with Lu-177-pentixather in Patient-Derived Xenograft (PDx) Models of Leukemia
    Schottelius, M.
    Habringer, S.
    Herhaus, P.
    Poschenrieder, A.
    Steiger, K.
    Schwaiger, M.
    Keller, U.
    Wester, H.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 : S50 - S50
  • [50] Development of patient-derived xenograft (PDX) models for pancreatic carcinoma as a preclinical platform for drug development
    Ricono, Jill
    Thatte, Jayant
    Scott, Colleen
    Broudy, Thomas B.
    CANCER RESEARCH, 2016, 76