Is PBEF/visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome?

被引：45
|
作者：
Sethi, Jaswinder K. [1 ]
机构：
[1] Univ Cambridge, Addenbrookes Hosp, Dept Clin Biochem, Cambridge CB2 2QR, England
来源：
CURRENT HYPERTENSION REPORTS | 2007年 / 9卷 / 01期
基金：
英国生物技术与生命科学研究理事会;
关键词：
D O I：
10.1007/s11906-007-0007-5
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Their dysregulated production in obesity has implicated them as important mediators in the pathogenesis of obesity-related risk factors for diabetes and cardiovascular disease. PBEF/visfatin/Nampt has recently been described as a novel adipokine with insulin mimetic properties. However, whether it is an authentic adipokine relevant to the metabolic syndrome remains a matter of some debate.
引用
收藏
页码：33 / 38
页数：6
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