In the present study, pods of Acacia nilotica mediated copper oxide nanoparticles (CuONPs) were synthesized and confirmed by spectroscopic, microscopic, and energy-dispersive X-ray (EDX) analysis. EDX analysis confirmed the presence of elements in the synthesized nanoparticles. FTIR analysis of synthesized nanoparticles revealed the presence of -C = C- the stretch of alkenes, primary and secondary alcohols (C-O stretch), and surface capping of phenolic groups. Results showed that biosynthesized nanoparticles exhibit significant antioxidant activity using DPPH assay and phosphomolybdate assay. Biofunctionalized nanoparticles possess a significant anticancer effect on HepG2 cancer cell line in a dose-dependent manner. CuONPs also showed thrombolytic activity, as they can dissolve the clot formed from the fresh blood. To the best of our knowledge, we report for the first time that Acacia nilotica pods mediated copper oxide nanoparticles exhibited various in vitro biological applications. (c) 2020 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the First International Conference on Frontiers in Chemical Sciences.
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King Saud Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Riyadh 11451, Saudi ArabiaSRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, India
Aboul-Soud, Mourad A. M.
Alqahtani, Mohammed S.
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King Saud Univ, Coll Pharm, Dept Pharmaceut, POB 2457, Riyadh 11451, Saudi ArabiaSRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, India
Alqahtani, Mohammed S.
Shahid, Mudassar
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King Saud Univ, Coll Pharm, Dept Pharmaceut, POB 2457, Riyadh 11451, Saudi ArabiaSRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, India
Shahid, Mudassar
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Syed, Rabbani
Lakshmipathy, R.
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SRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, IndiaSRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, India
Lakshmipathy, R.
Modigunta, Jeevan Kumar Reddy
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Korea Natl Univ Transportat, Chem Ind Inst, Dept Polymer Sci & Engn, Chungju 27469, South KoreaSRM Inst Sci & Technol, Directorate Learning & Dev, Kattankulathur 603203, Tamil Nadu, India