Post-Cardiac Arrest Encephalopathy

被引：23

作者：

Xiong, Wei ^{[1
]}

Hoesch, Robert E. ^{[2
]}

Geocadin, Romergryko G. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Neurosci Crit Care Div,Dept Neurosurg, Dept Neurol,Dept Anesthesiol & Crit Care Med, Baltimore, MD 21287 USA

[2] Univ Utah, Sch Med, Dept Neurol, Neurosci Crit Care,Clin Neurosci Ctr, Salt Lake City, UT USA

来源：

SEMINARS IN NEUROLOGY | 2011年 / 31卷 / 02期

关键词：

Cardiac arrest; anoxic; hypoxic; ischemic; hypoxic-ischemic; encephalopathy; NEURON-SPECIFIC ENOLASE; EMERGENCY CARDIOVASCULAR CARE; MILD THERAPEUTIC HYPOTHERMIA; AMERICAN-HEART-ASSOCIATION; CEREBRAL-ARTERY OCCLUSION; CENTRAL-NERVOUS-SYSTEM; ISCHEMIC BRAIN-INJURY; CARDIOPULMONARY-RESUSCITATION; EVOKED-POTENTIALS; POSTANOXIC COMA;

D O I：

10.1055/s-0031-1277991

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Brain injury continues to be a leading cause of mortality and morbidity in patients resuscitated after cardiac arrest. During periods of hypoxia and ischemia, numerous mechanisms contribute to the initial and secondary injury of the brain. Though many drugs and therapies have been evaluated for neuroprotection, only therapeutic hypothermia has been proven to be effective. Accurate prognostication after cardiac arrest is essential, and can be achieved with careful neurologic examination and several ancillary tests utilizing neurophysiology, neuroimaging, and biochemistry. Practice guidelines are now available for prognostication and postresuscitation care, with emphasis on improving survival and quality of life. Also reviewed are a wide spectrum of postarrest neurologic complications and their targeted treatments.

引用

页码：216 / 225

页数：10

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