Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China

被引:5
|
作者
Ge, Hongxia [1 ]
Liang, Yang [1 ]
Fang, Yingying [1 ]
Jin, Yi [1 ]
Su, Wenting [1 ]
Zhang, Guoqiang [2 ]
Wang, Jing [3 ]
Xiong, Hui [4 ]
Shang, Deya [5 ]
Chai, Yanfen [6 ]
Liu, Zhi [7 ]
Wei, Hongyan [8 ]
Wang, Hairong [9 ]
Zhang, Wei [10 ]
Ma, Fei [11 ]
Zhao, Wei [12 ]
Sun, Li [13 ]
Huang, Huan [14 ]
Ma, Qingbian [1 ]
机构
[1] Peking Univ Third Hosp, Emergency Dept, 49 North Garden Rd, Beijing 100191, Peoples R China
[2] China Japan Friendship Hosp, Emergency Dept, Beijing, Peoples R China
[3] Capital Med Univ, Xuanwu Hosp, Emergency Dept, Beijing, Peoples R China
[4] Peking Univ First Hosp, Emergency Dept, Beijing, Peoples R China
[5] Shandong Prov Hosp, Emergency Dept, Jinan, Shandong, Peoples R China
[6] Tianjin Med Univ, Gen Hosp, Emergency Dept, Tianjin, Peoples R China
[7] China Med Univ, Hosp 1, Emergency Dept, Shenyang, Liaoning, Peoples R China
[8] Sun Yat Sen Univ, Affiliated Hosp 1, Emergency Dept, Guangzhou, Guangdong, Peoples R China
[9] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Emergency Dept, Shanghai, Peoples R China
[10] Tianjin Third Cent Hosp, Emergency Dept, Tianjin, Peoples R China
[11] Guangdong Prov Peoples Hosp, Emergency Dept, Guangzhou, Guangdong, Peoples R China
[12] Air Force Med Univ, Xijing Hosp, Emergency Dept, Xian, Shaanxi, Peoples R China
[13] Shanxi Prov Peoples Hosp, Emergency Dept, Xian, Shaanxi, Peoples R China
[14] Qingdao Univ, Affiliated Hosp, Emergency Dept, Qingdao, Shandong, Peoples R China
关键词
Predictors; diagnosis; outcomes; acute kidney injury; acute decompensated heart failure; emergency department; WORSENING RENAL-FUNCTION; DISEASE; MANAGEMENT; GUIDELINE; OUTCOMES;
D O I
10.1177/03000605211016208
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objective This retrospective multicentre observational study was performed to assess the predictors of acute kidney injury (AKI) in patients with acute decompensated heart failure (ADHF) in emergency departments in China. Methods In total, 1743 consecutive patients with ADHF were recruited from August 2017 to January 2018. Clinical characteristics and outcomes were compared between patients with and without AKI. Predictors of AKI occurrence and underdiagnosis were assessed in multivariate regression analyses. Results Of the 1743 patients, 593 (34.0%) had AKI. AKI was partly associated with short-term all-cause mortality and cost. Cardiovascular comorbidities such as coronary heart disease, diabetes mellitus, and hypertension remained significant predictors of AKI in the univariate analysis. AKI was significantly more likely to occur in patients with a lower arterial pH, lower albumin concentration, higher creatinine concentration, and higher N-terminal pro-brain natriuretic peptide (NT-proBNP) concentration. Patients treated with inotropic agents were significantly more likely to develop AKI during their hospital stay. Conclusion This study suggests that cardiovascular comorbidities, arterial pH, the albumin concentration, the creatinine concentration, the NT-proBNP concentration, and use of inotropic agents are predictors of AKI in patients with ADHF.
引用
收藏
页数:12
相关论文
共 50 条