Unexpected Synthesis of N-Acyl Indolines via a Consecutive Cyclization of Iminophosphorane

被引：12

作者：

Li, Wen-Jing ^{[1
]}

Zhao, Fen-Fen ^{[1
]}

Ding, Ming-Wu ^{[1
]}

机构：

[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China

来源：

SYNLETT | 2011年 / 02期

基金：

中国国家自然科学基金;

关键词：

N-acyl indoline; iminophosphorane; cyclization; Staudinger reaction; ENANTIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; INDOLES; ROUTE; AMINATION; STRATEGY;

D O I：

10.1055/s-0030-1259280

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Acyl indolines were obtained unexpectedly from a consecutive cyclization of iminophosphorane in refluxing xylene or 1,2-dichlorobenzene in good yields. This new approach provides an efficient and direct access to the biologically important indolines which are further oxidizable to indoles and oxindoles.

引用

页码：265 / 267

页数：3

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