Gout: diagnosis, pathogenesis, and clinical manifestations

被引：53
|
作者：
Agudelo, CA
Wise, CM
机构：
[1] Virginia Commonwealth Univ, Med Coll Virginia, Div Rheumatol Allergy & Immunol, Dept Internal Med, Richmond, VA 23298 USA
[2] Emory Univ, Sch Med, Rheumatol Sect, Atlanta, GA 30322 USA
[3] Atlanta Vet Affiars Med Ctr, Decatur, GA USA
来源：
CURRENT OPINION IN RHEUMATOLOGY | 2001年 / 13卷 / 03期
关键词：
D O I：
10.1097/00002281-200105000-00015
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Gout is a common form of arthritis, in which many of the risk factors, pathogenetic mechanisms, and clinical features have been recognized for years. Nevertheless, new information has become available regarding the normal physiologic role of uric acid as an antioxidant, and greater insight has been obtained regarding the inflammatory process in acute gout, New studies have improved our understanding of the role of genetic and environmental factors responsible for hyperuricemia, and we know more about the significance of the association of hyperuricemia with other diseases. Clinically, rare complications and disease manifestations in new populations continue to be discussed, and diagnostic methods continue to be refined. (C) 2001 Lippincott Williams & Wilkins, Inc.
引用
收藏
页码：234 / 239
页数：6
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