Fe3O4 nanoparticles as an efficient and reusable catalyst for the solvent-free synthesis of 1H-indole and 1H-pyrrole derivatives

被引：13

作者：

Babaei, Seyyed Ebrahim ^{[1
]}

Hossaini, Zinatossadat ^{[1
]}

Besheli, Reza Ramezani ^{[1
]}

Tavakkoli, Vahid ^{[2
]}

机构：

[1] Islamic Azad Univ, Qaemshahr Branch, Dept Chem, POB 163, Qaemshahr, Iran

[2] Islamic Azad Univ, South Tehran Branch, Dept Chem, POB 11, Tehran, Iran

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2016年 / 52卷 / 05期

关键词：

activated acetylenic compounds; ethyl; 2-chloroacetoacetate; Fe3O4; nanoparticles; green synthesis; SOLID BASE CATALYST; BISINDOLE ALKALOIDS; POLYSUBSTITUTED PYRROLES; MULTICOMPONENT REACTIONS; SUBSTITUTED PYRROLES; ALDEHYDES; AMINES; WATER; IONS;

D O I：

10.1007/s10593-016-1880-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Magnetic Fe3O4 nanoparticles as a heterogeneous catalyst were found to be efficient for the synthesis of a series of pyrrole and indole derivatives using three-component reactions of primary amines, 1,3-dicarbonyl compounds, and activated acetylenic compounds under solvent-free conditions at room temperature. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification, and affordability of the catalyst.

引用

页码：294 / 298

页数：5

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