Synthesis of some new bioactive 1-N-subtituted 3,5-diaryl-2-pyrazolines

被引：0
|
作者：
Khan, Sadaf Sadiq [1 ]
Hasan, Aurangzeb [1 ]
机构：
[1] Quaid i Azam Univ, Dept Chem, Islamabad 45320, Pakistan
来源：
HETEROCYCLIC COMMUNICATIONS | 2007年 / 13卷 / 2-3期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A group of four series (A-D) of 22 new bioactive 1-N-acid substituted 3, 5-diphenyl-2-pyrazolines were synthesized by cyclization of variably substituted chalcones and simple or substituted phenyl hydrazine and / or semicarbazide, using acetic acid as a solvent. The chemical structure of the compounds was characterized by FTIR, (HNMR)-H-1, and EIMS spectroscopy and chemical analyses. The antifungal and antibacterial activities of these compounds were evaluated by agar tube dilution method and agar well diffusion method respectively.
引用
收藏
页码：131 / 138
页数：8
相关论文
共 50 条
  • [21] Synthesis of 1-carboxamido-3,5-diaryl-Δ2-pyrazolines and their antimicrobial study
    Kedar, RM
    ASIAN JOURNAL OF CHEMISTRY, 2001, 13 (02) : 477 - 480
  • [22] Enantioselective synthesis of bio-relevant 3,5-diaryl pyrazolines
    Mahe, Olivier
    Dez, Isabelle
    Levacher, Vincent
    Briere, Jean-Francois
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, 10 (19) : 3946 - 3954
  • [23] Synthesis and antimicrobial activities of 1-substituted-3,5-diaryl pyrazolines
    Jamode, VS
    Thakre, MDV
    ASIAN JOURNAL OF CHEMISTRY, 2003, 15 (03) : 1808 - 1810
  • [24] Photooxidation of 3,5-diaryl-1-phenyl-2-pyrazolines: Experimental and computational studies
    Soltani, Marzieh
    Memarian, Hamid Reza
    Sabzyan, Hassan
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2020, 389 (389)
  • [25] Synthesis and antidepressant activities of some 3,5-diphenyl-2-pyrazolines
    Palaska, E
    Aytemir, M
    Uzbay, IT
    Erol, D
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (06) : 539 - 543
  • [26] SYNTHESIS AND NMR-SPECTRA OF 3-(3,5-DIMETHYLFURYL-2)-1,5-DIARYL-DELTA-2-PYRAZOLINES
    BOLOGA, UL
    MUSAT, C
    GHEORGHIU, MD
    RACOVEANUSCHIKETANZ, A
    GHIVIRIGA, I
    BALABAN, AT
    ACH-MODELS IN CHEMISTRY, 1994, 131 (01): : 61 - 66
  • [27] Antibacterial activities of 3,5-diaryl-4-benzoyl-1-pyridoyl-Δ2-pyrazolines
    Kadu, MV
    Jamode, VS
    Tambekar, DH
    ASIAN JOURNAL OF CHEMISTRY, 1999, 11 (03) : 1064 - 1066
  • [28] Microwave assisted synthesis and antibacterial activity of some new 3,5-diaryl-2-isoxazolines
    Gahlot, US
    Rao, SS
    Jhala, YS
    Dulawat, SS
    Verma, BL
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 13 (02) : 111 - 114
  • [29] Synthesis and antibacterial activity of some 3,5-diphenyl and 1,3,5-triphenyl-2-pyrazolines
    Shinde, S
    Jadhav, W
    Rajendra, PB
    Bhusare, S
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2004, 51 (04) : 775 - 778
  • [30] SYNTHESIS OF SOME N,1-DIARYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINES AND N',1-DIARYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINES
    WU, MT
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1977, 14 (03) : 443 - 444
12345