Potentiation of melphalan-induced cytotoxicity through targeting of the base excision repair pathway in multiple myeloma

被引：0
|
作者：
Reed, April M. [1 ]
Fishel, Melissa L. [1 ]
Kelley, Markr R. [1 ]
Abonour, Rafat [2 ]
机构：
[1] Indiana Univ, Herman B Wells Ctr Pediat Res, Sch Med, Dept Pediat,Sect Hematol Oncol, Indianapolis, IN USA
[2] Indiana Univ, Sch Med, Indianapolis, IN USA
来源：
BLOOD | 2007年 / 110卷 / 11期
关键词：
D O I：
10.1182/blood.V110.11.4799.4799
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4799
引用
收藏
页码：273B / 273B
页数：1
相关论文
共 50 条
  • [21] Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex
    Patricia Gomez-Bougie
    Lisa Oliver
    Steven Le Gouill
    Régis Bataille
    Martine Amiot
    Oncogene, 2005, 24 : 8076 - 8079
  • [22] Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex
    Gomez-Bougie, P
    Oliver, L
    Le Gouill, S
    Bataille, R
    Amiot, M
    ONCOGENE, 2005, 24 (54) : 8076 - 8079
  • [23] Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induced Lymphodepletion in Patients with Multiple Myeloma: A Window for Adoptive Immunotherapy
    Condomines, Maud
    Veyrune, Jean-Luc
    Larroque, Marion
    Quittet, Philippe
    Latry, Pascal
    Lugagne, Cecile
    Hertogh, Catherine
    Kanouni, Tarik
    Rossi, Jean-Francois
    Klein, Bernard
    JOURNAL OF IMMUNOLOGY, 2010, 184 (02): : 1079 - 1084
  • [24] Base excision repair inhibition sensitizes mammalian cells to iododeoxyuridine-induced cytotoxicity and radiosensitivity.
    Taverna, P
    Hwang, H
    Session, NN
    Reddy, G
    Zarling, D
    Kinsella, TJ
    CLINICAL CANCER RESEARCH, 2001, 7 (11) : 3788S - 3789S
  • [25] Targeting Tryptophan Catabolic Kynurenine Pathway Enhances Anti-Tumor Immunity and Cytotoxicity in Multiple Myeloma
    Ray, Arghya
    Song, Yan
    Chauhan, Dharminder
    Anderson, Kenneth C.
    BLOOD, 2018, 132
  • [26] Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells
    Couve-Privat, Sophie
    Mace, Gaetane
    Rosselli, Filippo
    Saparbaev, Murat K.
    NUCLEIC ACIDS RESEARCH, 2007, 35 (17) : 5672 - 5682
  • [27] Nanoparticle-induced inflammation and its effect on the base excision repair pathway in rat lungs
    Wessels, A.
    Albrecht, C.
    Knaapen, A. M.
    Duffin, R.
    van Berlo, D.
    Voss, P.
    Unfried, K.
    Schins, R. P. F.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2007, 375 : 86 - 87
  • [28] Nanoparticle-induced inflammation and its effect on the base excision repair pathway in rat lungs
    Wessels, Anton
    Albrecht, Catrin
    Knaapen, Ad
    Duffin, Rodger
    van Berlo, Damien
    Voss, Peter
    Unfried, Klaus
    Schins, Roel
    TOXICOLOGY LETTERS, 2007, 172 : S175 - S175
  • [29] Enhanced survival and adherence of melphalan-induced senescent-like dormant multiple myeloma cells co-cultured with bone marrow stromal cells
    Guilatco, Angelo J.
    Borges, Gabriel Alvares
    Tchkonia, Tamar
    Kirkland, James L.
    Kourelis, Taxiarchis
    Drake, Matthew T.
    Weivoda, Megan
    CANCER RESEARCH, 2023, 83 (02)
  • [30] Enhanced Survival and Adherence of Melphalan-Induced Senescent-like Dormant Multiple Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells
    Guilatco, Angelo Jose
    Borges, Gabriel Alvares
    Tchkonia, Tamar
    Kirkland, James L.
    Kourelis, Taxiarchis
    Drake, Matthew T.
    Weivoda, Megan
    BLOOD, 2022, 140 : 12434 - 12435
12345