Potentiation of melphalan-induced cytotoxicity through targeting of the base excision repair pathway in multiple myeloma

被引：0
|
作者：
Reed, April M. [1 ]
Fishel, Melissa L. [1 ]
Kelley, Markr R. [1 ]
Abonour, Rafat [2 ]
机构：
[1] Indiana Univ, Herman B Wells Ctr Pediat Res, Sch Med, Dept Pediat,Sect Hematol Oncol, Indianapolis, IN USA
[2] Indiana Univ, Sch Med, Indianapolis, IN USA
来源：
BLOOD | 2007年 / 110卷 / 11期
关键词：
D O I：
10.1182/blood.V110.11.4799.4799
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4799
引用
收藏
页码：273B / 273B
页数：1
相关论文
共 50 条
  • [1] Investigation of the role of base excision repair of melphalan-induced DNA damage
    Helsby, Nuala
    van Kan, Maia
    Burns, Kathryn
    BRITISH JOURNAL OF PHARMACOLOGY, 2023, 180 : 1171 - 1171
  • [2] The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells
    Chen, Q
    Van der Sluis, PC
    Boulware, D
    Hazlehurst, LA
    Dalton, WS
    BLOOD, 2005, 106 (02) : 698 - 705
  • [3] Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells
    Efferth, T
    Fabry, U
    Osieka, R
    ANTICANCER RESEARCH, 2002, 22 (1A) : 231 - 234
  • [4] Melphalan-induced DNA damage in vitro as a predictor for clinical outcome in multiple myeloma
    Dimopoulos, Meletios A.
    Souliotis, Vassilis L.
    Anagnostopoulos, Athanasios
    Bamia, Christina
    Pouli, Anastasia
    Baltadakis, Ioannis
    Terpos, Evangelos
    Kyrtopoulos, Soterios A.
    Sfikakis, Petros P.
    HAEMATOLOGICA, 2007, 92 (11) : 1505 - 1512
  • [5] Melphalan-induced DNA damage in vitro as predictor for clinical outcome in multiple myeloma.
    Dimopoulos, Meletios A.
    Souliotis, Vassilis L.
    Anagnostopoulos, Athanasios
    Bamia, Christina
    Pouli, Anastasia
    Baltadakis, Ioannis
    Terpos, Evangelos
    Kyrtopoulos, Soterios A.
    Sfikakis, Petros P.
    BLOOD, 2006, 108 (11) : 22A - 23A
  • [6] An Inverse Switch in DNA Base Excision and Strand Break Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells
    Sousa, Mirta M. L.
    Zub, Kamila Anna
    Aas, Per Arne
    Hanssen-Bauer, Audun
    Demirovic, Aida
    Sarno, Antonio
    Tian, Erming
    Liabakk, Nina B.
    Slupphaug, Geir
    PLOS ONE, 2013, 8 (02):
  • [7] Panobinostat Potentiates Melphalan-Induced Apoptosis of Myeloma Cells and Minimizes Untoward Side Effects in Multiple Myeloma
    Gkotzamanidou, Maria
    Souliotis, Vassilis L.
    Dimopoulos, Meletios A.
    Terpos, Evangelos
    BLOOD, 2019, 134
  • [8] Melphalan-Induced Multiple Myeloma Cells Exhibit a Senescent-like Dormant Phenotype
    Guilatco, Angelo Jose
    Borges, Gabriel Alvares
    Sannuli, Neal I.
    Tchkonia, Tamar
    Kirkland, James L.
    Kourelis, Taxiarchis
    Drake, Matthew T.
    Weivoda, Megan
    BLOOD, 2023, 142
  • [9] Overcoming Melphalan Resistance By Targeting Crucial DNA Repair Pathways in Multiple Myeloma
    Patel, Pritesh Rajni
    Senyuk, Vitalyi
    Sweiss, Karen
    Calip, Gregory
    Oh, Annie
    Mahmud, Nadim
    Rondelli, Damiano
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020, 26 (03) : S224 - S225
  • [10] The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)
    Ino, Rumi
    Saitoh, Takayuki
    Kitamura, Yuya
    Homma, Kazuki
    Takahashi, Noriyuki
    Nanami, Gotoh
    Kasamatsu, Tetsuhiro
    Shimizu, Hiroaki
    Takizawa, Makiko
    Matsumoto, Morio
    Sawamura, Morio
    Yokohama, Akihiko
    Tsukamoto, Norifumi
    Handa, Hiroshi
    Murakami, Hirokazu
    BLOOD, 2017, 130
12345