Synthesis of the enantiomer of nelarabine

被引：8
|
作者：
Herbal, K [1 ]
Kitteringham, J [1 ]
Voyle, M [1 ]
Whitehead, AJ [1 ]
机构：
[1] GlaxoSmithKline, Synth Chem, Stevenage SG1 2NY, Herts, England
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 17期
关键词：
nelarabine; enantiomer; nucleosides; Vorbruggen;
D O I：
10.1016/j.tetlet.2005.03.039
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A synthesis of the enantiomer of nelarabine is described. Subtle changes in the protecting group strategy allow for an efficient inversion of the C-2' stereocentre. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2961 / 2964
页数：4
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