MEDI 509-Discovery and development of novel BACE-1 inhibitors: Substituted piperidine analogs

被引：0

作者：

Wu, Yusheng ^{[1
]}

Stamford, Andrew ^{[1
]}

Cumming, Jared ^{[1
]}

Iserloh, Ulrich ^{[1
]}

Greenlee, William ^{[1
]}

Kennedy, Matthew ^{[1
]}

Chen, Xia ^{[1
]}

Kuvelkar, Reshma ^{[1
]}

McHugh, Nansie ^{[1
]}

Voigt, Johannes ^{[1
]}

Strickland, Corey ^{[1
]}

Favreau, Leonard ^{[1
]}

Li, Cheng ^{[1
]}

Liu, TongTong ^{[1
]}

Chan, Tze-Ming ^{[1
]}

Osterman, Rebecca ^{[1
]}

机构：

[1] Schering Plough Res Inst, Kenilworth, NJ 07033 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 232卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

509-MEDI

引用

页数：1

共 50 条

[31] High throughput virtual screening and E-pharmacophore filtering in the discovery of new BACE-1 inhibitors
Karthikeyan Muthusamy
Kh. Dhanachandra Singh
Sathishkumar Chinnasamy
Selvaraman Nagamani
Gopinath Krishnasamy
Chinnaiyan Thiyagarajan
Palanisamy Premkumar
Muthuswamy Anusuyadevi
Interdisciplinary Sciences: Computational Life Sciences, 2013, 5 : 119 - 126
[32] Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE-1 and GSK-3β Inhibitors
Prati, Federica
De Simone, Angela
Bisignano, Paola
Armirotti, Andrea
Summa, Maria
Pizzirani, Daniela
Scarpelli, Rita
Perez, Daniel I.
Andrisano, Vincenza
Perez-Castillo, Ana
Monti, Barbara
Massenzio, Francesca
Polito, Letizia
Racchi, Marco
Favia, Angelo D.
Bottegoni, Giovanni
Martinez, Ana
Bolognesi, Maria Laura
Cavalli, Andrea
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (05) : 1578 - 1582
[33] High throughput virtual screening and E-pharmacophore filtering in the discovery of new BACE-1 inhibitors
Muthusamy, Karthikeyan
Singh, Kh. Dhanachandra
Chinnasamy, Sathishkumar
Nagamani, Selvaraman
Krishnasamy, Gopinath
Thiyagarajan, Chinnaiyan
Premkumar, Palanisamy
Anusuyadevi, Muthuswamy
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2013, 5 (02) : 119 - 126
[34] P2′-truncated BACE-1 inhibitors with a novel hydroxethylene-like core
Meredith, Jenny Adrian
Bjorklund, Catarina
Adolfsson, Hans
Jansson, Katarina
Hallberg, Anders
Rosenquist, Asa
Samuelsson, Bertil
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (02) : 542 - 554
[35] Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1
Barrow, James C.
Rittle, Kenneth E.
Ngo, Phung L.
Selnick, Harold G.
Graham, Samuel L.
Pitzenberger, Steven M.
McGaughey, Georgia B.
Colussi, Dennis
Lai, Ming-Tain
Huang, Qian
Tugusheva, Katherine
Espeseth, Amy S.
Simon, Adam J.
Munshi, Sanjeev K.
Vacca, Joseph P.
CHEMMEDCHEM, 2007, 2 (07) : 995 - 999
[36] Discovery and development of pyrrolidinoiminopyrimidinones as potent and selective BACE1 inhibitors
Zhu, Zhaoning
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
[37] MEDI 49-Novel analogs as 11β-HSD1 inhibitors
Shah, Unmesh
Boyle, Craig D.
Chackalamannil, Samuel
Baker, Hana
Kowalski, Timothy
Zhang, Lili
Terracina, Giuseppe
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234
[38] BACE-1 hydroxyethylamine inhibitors using novel edge-to-face interaction with Arg-296
Clarke, Brian
Cutler, Leanne
Demont, Emmanuel
Dingwall, Colin
Dunsdon, Rachel
Hawkins, Julie
Howes, Colin
Hussain, Ishrut
Maile, Graham
Matico, Rosalie
Mosley, Julie
Naylor, Alan
O'Brien, Alistair
Redshaw, Sally
Rowland, Paul
Soleil, Virginie
Smith, Kathrine J.
Sweitzer, Sharon
Theobald, Pam
Vesey, David
Walter, Daryl S.
Wayne, Gareth
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (15) : 4639 - 4644
[39] MEDI 508-Design and development of cyclic amine BACE1 inhibitors: An overview
Cumming, Jared
Wang, Lingyan
Babu, Suresh
Carroll, Carolyn
Chen, Xia
Gaspari, Paul
Greenlee, William
Guo, Tao
Hobbs, Doug
Huang, Ying
Iserloh, Ulrich
Kennedy, Matthew
Kuvelkar, Reshma
Thuy Le
Li, Guoqing
Lowrie, Jeffrey
Ozgur, Lynne
Pan, Jianping
Saionz, Kurt
Strickland, Corey
Stamford, Andrew
Tadesse, Dawit
Voigt, Johannes
Wu, Yusheng
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
[40] MEDI 401-Discovery of anilinothiazolone analogs as 11beta-HSD1 inhibitors
Yuan, Chester
St Jean, David J., Jr.
Liu, Qingyian
Cai, Lynn
Li, Aiwen
Han, Nianhe
Askew, Ben
Hungate, Randall
Johansson, Lars
Tedenborg, Lars
Pyring, David
Williams, Meredith
Wang, Minghan
Hale, Clarence
Zhang, Jiandong
Jordan, Steven
Bartberger, Michael
Sun, Yaxiong
Emery, Maurice
Fotsch, Christopher H.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232

← 1 2 3 4 5 →