From plant to drug: ionic liquids for the reactive dissolution of biomass

被引：45
|
作者：
Ressmann, Anna K. [1 ]
Gaertner, Peter [1 ]
Bica, Katharina [1 ]
机构：
[1] Vienna Univ Technol, Inst Appl Synthet Chem, A-1040 Vienna, Austria
来源：
GREEN CHEMISTRY | 2011年 / 13卷 / 06期
关键词：
OSELTAMIVIR PHOSPHATE TAMIFLU(TM); SHIKIMIC ACID; ESTERIFICATION; CATALYSTS; EXTRACTION;
D O I：
10.1039/c1gc15058h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present an ionic liquid (IL) strategy for the reactive dissolution of star anise seeds using different Bronsted-acidic ionic liquids as the solvent and reaction media towards the isolation of important pharmaceutical intermediates; this procedure provides a single-step, higher yielding and environmentally benign strategy towards the synthesis of the anti-influenza drug Tamiflu (TM).
引用
收藏
页码：1442 / 1447
页数：6
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