Neuroimaging of multiple sclerosis

Introduction. Multiple sclerosis is currently considered to be a destructive disorder and a certain degree of alteration in immunity is considered to occur in genetically susceptible persons. Development. Magnetic resonance (MR) has become the basic technique for diagnosis a,ld evaluation of the response to treatment. The key factor in the information obtained from MR images is the water content. There are several technical situations to be taken into account when using MR in multiple sclerosis: phase T-1, phase T-2, FLAIR, phase T-1 with gadolinum, MR with spectroscopy, cerebral parenchymatous fraction and magnetization transfer MR, Apart from magnetic resonance immunological changes of multiple sclerosis are seen in the CSF in over 50% of the patients with the disorder. Use of evoked potentials, with the important advantage of detecting lesions not visible on MR and asymptomatic lesions, may also be useful for establishment of the diagnosis. Conclusion. In this article we describe the rise of neuroimaging in the diagnosis of multiple sclerosis.