Metal-Free Intramolecular Amination: One-Pot Tandem Synthesis of 3-Substituted 4-Quinolones

被引：15

作者：

Liu, Qi-Lun ^{[1
]}

Li, Qiu-Lian ^{[1
]}

Fei, Xiang-Dong ^{[1
]}

Zhu, Yong-Ming ^{[1
]}

机构：

[1] Soochow Univ, Coll Pharm, Suzhou 215123, Peoples R China

来源：

ACS COMBINATORIAL SCIENCE | 2011年 / 13卷 / 01期

基金：

中国国家自然科学基金;

关键词：

quinolones; metal-free; one-pot; intramolecular amination; CROSS-COUPLING REACTIONS; DERIVATIVES; CYCLIZATION; INHIBITORS; QUINOLONE; CATALYST;

D O I：

10.1021/co1000103

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

3-Substituted 4-quinolones were synthesized using a one-pot metal-free strategy in moderate to quantitative yields. Carried out in dimethylsulfoxide (DMSO) via a sequential addition of materials, the methodology is tolerant of a wide range of functional groups and applicable to library synthesis.

引用

页码：19 / 23

页数：5

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