Obesity and inflammation: the adipocytokines

被引：0
|
作者：
Vidal, H [1 ]
机构：
[1] RTH Laennec, INSERM, U449, F-69372 Lyon 08, France
来源：
ANNALES D ENDOCRINOLOGIE | 2003年 / 64卷 / 05期
关键词：
adipocytes; cytokines; insulin resistance; C-reactive protein; interleukins; leptin;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It is now well documented that obesity is associated with a chronic, low grade, inflammatory state. The serum concentrations of a number of inflammatory markers, such as CRP, fibrinogene or serum amyloids are increased in obese subjects. More importantly, the levels of several pro-inflammatory cytokines, including TNFalpha, IL-6 and leptin are significantly higher in the plasma of obese patients. We will review here the possible role of adipose tissue and the production of adipocyte-derived cytokines in this inflammatory state. The observed increase in the concentrations of these adipocytokines is now suspected to play a determinant role in the development of most of the complications of obesity.
引用
收藏
页码：S40 / S44
页数：5
相关论文
共 50 条
  • [31] Clinical characteristics, airway inflammation, and adipocytokines in overweight and obese asthmatics
    Ishii, Masanobu
    Miyamoto, Yukari
    Ochiai, Katsunori
    Kirishi, Saori
    Tagaya, Etsuko
    Takeyama, Kiyoshi
    Tamaoki, Jun
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2013, 42
  • [32] Metabolic Syndrome, Adipocytokines and Inflammation in Sjogren's Syndrome.
    Augusto, Kristopherson Lustosa
    Bonfa, Eloisa
    Pereira, Rosa M. R.
    Bueno, Cleonice
    Viana, Vilma S. T.
    Pasoto, Sandra G.
    [J]. ARTHRITIS & RHEUMATOLOGY, 2014, 66 : S1281 - S1282
  • [33] Molecular mechanism of obesity-related diseases: importance of adipocytokines
    Matsuzawa, Y
    Funahashi, T
    Kuriyama, H
    Kihara, S
    [J]. COMMON DISEASE: GENETIC AND PATHOGENETIC ASPECTS OF MULTIFACTORIAL DISEASES, 1999, 1181 : 37 - 43
  • [34] Obesity as a risk factor for Alzheimer’s disease: the role of adipocytokines
    Liliana Letra
    Isabel Santana
    Raquel Seiça
    [J]. Metabolic Brain Disease, 2014, 29 : 563 - 568
  • [35] THE ROLE OF OBESITY AND PLASMA ADIPOCYTOKINES IN IMMUNE DYSREGULATION IN SEPSIS PATIENTS
    de Nooijer, Aline H.
    Antonakos, Nikolaos
    Markopoulou, Dimitra
    Grondman, Inge
    Kox, Matthijs
    Pickkers, Peter
    Giamarellos-Bourboulis, Evangelos J.
    Netea, Mihai G.
    [J]. SHOCK, 2023, 59 (03): : 344 - 351
  • [36] ADIPOCYTOKINES: NOVEL THERAPEUTIC TARGETS IN ENDOTHELIAL DYSFUNCTION AND VASCULAR INFLAMMATION?
    Peiro, C.
    [J]. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2017, 121 : 19 - 19
  • [37] Obesity and inflammation
    Karczewski, Jacek
    Sledzinska, Ewelina
    Baturo, Alina
    Jonczyk, Izabela
    Maleszko, Aleksander
    Samborski, Pawel
    Begier-Krasinska, Beata
    Dobrowolska, Agnieszka
    [J]. EUROPEAN CYTOKINE NETWORK, 2018, 29 (03) : 83 - 94
  • [38] Obesity and inflammation
    Jacek Karczewski
    Ewelina Śledzińska
    Alina Baturo
    Izabela Jończyk
    Aleksander Maleszko
    Paweł Samborski
    Beata Begier-Krasińska
    Agnieszka Dobrowolska
    [J]. European Cytokine Network, 2018, 29 : 83 - 94
  • [39] Obesity and inflammation
    Graessler, J.
    Blueher, M.
    Chavakis, T.
    [J]. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2013, 138 (05) : 172 - 175
  • [40] Impact of child obesity on adipose tissue physiology: assessment of adipocytokines and inflammatory cytokines as biomarkers of obesity
    Leoni, Maria Chiara
    Valsecchi, Chiara
    Mantelli, Melissa
    Marastoni, Laura
    Tinelli, Carmine
    Marchi, Antonietta
    Castellazzi, Annamaria
    [J]. PEDIATRIC REPORTS, 2010, 2 (02) : 62 - 66
12345