Study of solubility of copoly (L-lactic acid/glycolic acid) by direct melt polycondensation

被引：0
|
作者：
Lan, P [1 ]
Hu, XC [1 ]
机构：
[1] Jiaxing Univ, Zhejiang 314001, Peoples R China
来源：
Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials (ICAFPM 2005), Vol 1 and 2: NEW CENTURY , NEW MATERIALS AND NEW LIFE | 2005年
关键词：
lactic acid/glycolic acid; melt polymerization; direct method; solubility;
D O I：
暂无
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
A two steps direct copolymerisation process of L-lactic acid(L-LA)/glycilic acid(GA) was developed. The first step is to produce oligomer of L-LA/GA and then the oligomer was polymerized with binary catalyst tin chloride dihydrate/p-toluenesulfonic acid. In this way, the copoly(L-LA/GA) (PLGA) without any organic solvent was synthesized directly. The solubility in chloroform of PLGA were studied by nuclear magnetic resonance (NMR). The results show that the solubility of PLGA in chloroform decreases with the increase of the average lengths of the glycolic acid units (LG).
引用
收藏
页码：916 / 919
页数：4
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