Exploring P-Glycoprotein Substrate Access

被引:0
|
作者
Domicevica, Laura [1 ]
Biggin, Philip C. [1 ]
机构
[1] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England
关键词
D O I
10.1016/j.bpj.2014.11.806
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
727-Pos
引用
收藏
页码:146A / 146A
页数:1
相关论文
共 50 条
  • [21] IS INHIBITION OF P-GLYCOPROTEIN (P-GP) SUBSTRATE DEPENDENT?
    Louie, Steven W.
    Hsiao, Peng
    Unadkat, Jashvant D.
    DRUG METABOLISM REVIEWS, 2014, 45 : 252 - 253
  • [22] Is aspirin a substrate of MDR1/P-glycoprotein?
    Singh, Renu
    Naik, Tanvi
    Nigam, Anuja
    Chatterjee, Sagnik
    Rajanna, Prabhakar
    Shen Hong
    Iyer, Ramaswamy
    XENOBIOTICA, 2020, 50 (10) : 1258 - 1264
  • [23] Cyclodextrins Enhances the Intestinal Permeability of P-Glycoprotein Substrate
    AL-Mohizea, Abdullah M.
    Zawaneh, Feras
    Alam, Mohd Aftab
    AL-Jenoobi, Fahad I.
    EL-Maghraby, Gamal M.
    LATIN AMERICAN JOURNAL OF PHARMACY, 2015, 34 (02): : 319 - 326
  • [24] Effect of pharmaceutical excipients on the permeability of P-glycoprotein substrate
    Al-Mohizea, A. M.
    Zawaneh, F.
    Alam, M. A.
    Al-Jenoobi, F. I.
    El-Maghraby, G. M.
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2014, 24 (05) : 491 - 495
  • [25] Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
    Weidner, Lora D.
    Fung, King Leung
    Kannan, Pavitra
    Moen, Janna K.
    Kumar, Jeyan S.
    Mulder, Jan
    Innis, Robert B.
    Gottesman, Michael M.
    Hall, Matthew D.
    DRUG METABOLISM AND DISPOSITION, 2016, 44 (02) : 275 - 282
  • [26] In Silico Characterization of P-Glycoprotein Substrate Entrance Pathways
    Domicevica, Laura
    Paramo, Teresa
    Biggin, Philip C.
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 141A - 141A
  • [27] Simotinib as a modulator of P-glycoprotein: substrate, inhibitor, or inducer?
    Huang, Lingling
    Shen, Cheng
    Chen, Yanfen
    Yan, Huiwen
    Cheng, Zeneng
    Zhu, Qubo
    ANTI-CANCER DRUGS, 2016, 27 (04) : 300 - 311
  • [28] Exploring the Chemical Space of P-Glycoprotein Interacting Compounds
    Prachayasittikul, Veda
    Mandi, Prasit
    Prachayasittikul, Supaluk
    Prachayasittikul, Virapong
    Nantasenamat, Chanin
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 17 (14) : 1332 - 1345
  • [29] Development of Simplified in Vitro P-Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P-Glycoprotein
    Ohashi, Rikiya
    Watanabe, Reiko
    Esaki, Tsuyoshi
    Taniguchi, Tomomi
    Torimoto-Katori, Nao
    Watanabe, Tomoko
    Ogasawara, Yuko
    Takahashi, Tsuyoshi
    Tsukimoto, Mikiko
    Mizuguchi, Kenji
    MOLECULAR PHARMACEUTICS, 2019, 16 (05) : 1851 - 1863
  • [30] Effect of P-glycoprotein on the ocular disposition of a model substrate, quinidine
    Duvvuri, S
    Gandhi, MD
    Mitra, AK
    CURRENT EYE RESEARCH, 2003, 27 (06) : 345 - 353