Two New Ginkgolides from the Leaves of Ginkgo biloba

被引：36
|
作者：
Liao, Hua-Jun [1 ]
Zheng, Yun-Feng [1 ]
Li, Hong-Yang [1 ]
Peng, Guo-Ping [1 ]
机构：
[1] Nanjing Univ Chinese Med, Coll Pharm, Nanjing 210029, Peoples R China
来源：
PLANTA MEDICA | 2011年 / 77卷 / 16期
关键词：
Ginkgoaceae; Ginkgo biloba L; ginkgolide P; ginkgolide Q; platelet activating factor;
D O I：
10.1055/s-0030-1271153
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new diterpenoid compounds, ginkgolide P (1) and ginkgolide Q (2), were isolated from the leaves of Ginkgo biloba L. Their structures were elucidated by various spectroscopic methods, and the structure of 1 was further confirmed by X-ray crystallographic analysis. The activities of the compounds were evaluated against platelet aggregation induced by platelet activating factor (PAF), and the preliminary structure-activity relationship was also discussed.
引用
收藏
页码：1818 / 1821
页数：4
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