Clinical use of E-coli Nissle 1917 in inflammatory bowel disease

被引：207
|
作者：
Schultz, Michael [1 ]
机构：
[1] Univ Otago, Sch Med, Dept Med & Surg Sci, Med Sect, Dunedin, New Zealand
来源：
INFLAMMATORY BOWEL DISEASES | 2008年 / 14卷 / 07期
关键词：
E. coli Nissle 1917; 5-ASA; clinical use; probiotics; inflammatory bowel disease;
D O I：
10.1002/ibd.20377
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The probiotic Escherichia coli strain Nissle 1917 is in addition to some Lactobacilli sp. one of the best-studied probiotic strains. This particular E. coli strain was isolated in 1917 based on its potential to protect from presumably infectious gastroenteritis. Initial therapeutic success was noted in the management of gastrointestinal infectious disorders and infections affecting the urinary tract; the focus shifted later to chronic inflammatory conditions. The unique combination of fitness and survival factors to support intestinal survival, the lack of virulence, and obvious probiotic properties make this microorganism a safe and effective candidate in the treatment of chronic inflammatory bowel diseases. Three large clinical trials have assessed the potential in the maintenance of remission of ulcerative colitis and equivalence to standard 5-ASA medication was documented. This review aims to discuss important mechanisms of E coli Nissle 1917 and will review the available literature regarding treatment of inflammatory bowel diseases.
引用
收藏
页码：1012 / 1018
页数：7
相关论文
共 50 条
  • [41] Plasmid Vectors for in Vivo Selection-Free Use with the Probiotic E. coli Nissle 1917
    Kan, Anton
    Gelfat, Ilia
    Emani, Sivaram
    Praveschotinunt, Pichet
    Joshi, Neel S.
    ACS SYNTHETIC BIOLOGY, 2021, 10 (01): : 94 - 106
  • [42] Genetic engineering of probiotic Escherichia coli Nissle 1917 for clinical application
    Bingming Ou
    Ying Yang
    Wai Liang Tham
    Lin Chen
    Jitao Guo
    Guoqiang Zhu
    Applied Microbiology and Biotechnology, 2016, 100 : 8693 - 8699
  • [43] Genetic engineering of probiotic Escherichia coli Nissle 1917 for clinical application
    Ou, Bingming
    Yang, Ying
    Tham, Wai Liang
    Chen, Lin
    Guo, Jitao
    Zhu, Guoqiang
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100 (20) : 8693 - 8699
  • [44] Effect of orally administered probiotic E-coli strain Nissle 1917 on intestinal mucosal immune cells of healthy young pigs
    Duncker, Swantje C.
    Lorentz, Axel
    Schroeder, Bernd
    Breves, Gerhard
    Bischoff, Stephan C.
    VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2006, 111 (3-4) : 239 - 250
  • [45] Adherence properties of the probiotic E-coli strain Nissle 1917 with regard to human gut biopsies and human epithelial cell lines
    Troge, A.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 299 : 94 - 94
  • [46] Evidence-based therapy with E. coli Nissle 1917 in paediatrics
    Stroff, T.
    Mueller, M.
    KLINISCHE PADIATRIE, 2008, 220 (02): : 109 - 110
  • [47] Seroreactivity to E-coli outer membrane protein C antibodies in active inflammatory bowel disease; diagnostic value and correlation with phylogroup B2 E-coli infection
    Petersen, Andreas Munk
    Schou, Christian
    Mirsepasi, Hengameh
    Engberg, Jorgen
    Friis-Moller, Alice
    Nordgaard-Lassen, Inge
    Wildt, Signe
    Krogfelt, Karen Angeliki
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2012, 47 (02) : 155 - 161
  • [48] Co-localisation of E-coli with macrophages in lamina propria in patients with active inflammatory bowel disease (IBD)
    Rayment, N
    Mylonaki, M
    Rampton, D
    Hudspith, B
    Brostoff, J
    GASTROENTEROLOGY, 2003, 124 (04) : A479 - A479
  • [49] Gradient Magnetic Field Accelerates Division of E. coli Nissle 1917
    Gorobets, Svitlana
    Gorobets, Oksana
    Sharai, Iryna
    Polyakova, Tatyana
    Zablotskii, Vitalii
    CELLS, 2023, 12 (02)
  • [50] Antagonistic effects of E. coli Nissle 1917 on various EHEC strains
    Rund, S.
    Rohde, H.
    Oelschlaeger, T.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2012, 302 : 96 - 96
12345