Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease

被引：0

作者：

Mandat, Tomasz ^{[1
,2
]}

Koziara, Henryk ^{[1
,2
]}

Nauman, Pawel ^{[1
,2
]}

Tykocki, Tomasz ^{[2
]}

Bonicki, Wieslaw ^{[1
,2
]}

机构：

[1] Maria Curie Sklodowska Oncol Ctr, Dept Neurosurg, PL-02781 Warsaw, Poland

[2] Inst Psychiat & Neurol, Dept Neurosurg, Warsaw, Poland

来源：

BIOCYBERNETICS AND BIOMEDICAL ENGINEERING | 2011年 / 31卷 / 03期

关键词：

deep brain stimulation; subthalamic nucleus; Parkinson's disease; GLOBUS-PALLIDUS; FAILURE;

D O I：

10.1016/S0208-5216(11)70018-3

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A group of 37 patients diagnosed with Parkinson's disease (PD) were treated with subthalamic deep brain stimulation (STN DBS). The mean age at implantation was 59 +/- 11 years and PD has been present from 6 to 17 years (mean 9). The STN was identified by direct and indirect methods: macro stimulation and microrecording in all cases. At a three month follow-up, the authors observed a mean reduction of 49% in UPDRS II score and a mean reduction of 65% in UPDRS III score. Mean reduction of 1-dopa consumption was 62%. The authors concluded that STN DBS safely reduces disabling symptoms of PD.

引用

页码：47 / 55

页数：9

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