Nonlinear effects of noradrenergic modulation of olfactory bulb function in adult rodents

被引:50
|
作者
Linster, Christiane [1 ]
Nai, Qiang [2 ]
Ennis, Matthew [2 ]
机构
[1] Cornell Univ, Dept Neurobiol & Behav, Computat Physiol Lab, Ithaca, NY 14853 USA
[2] Univ Tennessee, Ctr Hlth Sci, Dept Anat & Neurobiol, Memphis, TN 38163 USA
基金
美国国家卫生研究院;
关键词
computation; neuromodulation; LOCUS-COERULEUS NEURONS; AUDITORY-CORTEX NEURONS; FIELD CORTICAL-NEURONS; MOVING VISUAL-STIMULI; LONG-TERM ENHANCEMENT; MITRAL CELLS; DENDRODENDRITIC INHIBITION; SYNCHRONIZED OSCILLATIONS; CHOLINERGIC MODULATION; SYNAPTIC-TRANSMISSION;
D O I
10.1152/jn.00960.2010
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Linster C, Nai Q, Ennis M. Nonlinear effects of noradrenergic modulation of olfactory bulb function in adult rodents. J Neurophysiol 105: 1432-1443, 2011. First published January 27, 2011; doi: 10.1152/jn.00960.2010.-The mammalian main olfactory bulb receives a significant noradrenergic input from the locus coeruleus. Norepinephrine (NE) is involved in acquisition of conditioned odor preferences in neonatal animals, in some species-specific odor-dependent behaviors, and in adult odor perception. We provide a detailed review of the functional role of NE in adult rodent main olfactory bulb function. We include cellular, synaptic, network, and behavioral data and use computational simulations to tie these different types of data together.
引用
收藏
页码:1432 / 1443
页数:12
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