Clinical Features in Children With Kawasaki Disease Shock Syndrome: A Systematic Review and Meta-Analysis

被引:7
|
作者
Zheng, Zhimin [1 ]
Huang, Yanzhi [2 ]
Wang, Zhiyi [1 ]
Tang, Jia [1 ]
Chen, Xiaoqian [1 ]
Li, Ying [1 ]
Li, Meng [1 ]
Zang, Chengye [1 ]
Wang, Yibo [2 ]
Wang, Liwu [2 ]
Ma, Yingwei [2 ]
Sun, Liwei [2 ]
机构
[1] Changchun Univ Chinese Med, Coll Clin Med, Changchun, Peoples R China
[2] Childrens Hosp Changchun, Jilin Childrens Med Ctr, Changchun, Peoples R China
来源
关键词
Kawasaki disease; shock; Kawasaki disease shock syndrome; clinical feature; meta-analysis; LONG-TERM MANAGEMENT; HEALTH-PROFESSIONALS; MANIFESTATIONS; STATEMENT; DIAGNOSIS;
D O I
10.3389/fcvm.2021.736352
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: This study aimed to identify the clinical features of Kawasaki disease shock syndrome (KDSS) in children.Methods: The case-control studies of KDSS and KD children up until April 30, 2021 were searched in multiple databases. The qualified research were retrieved by manually reviewing the references. Review Manager 5.3 software was used for statistical analysis.Results: The results showed that there was no significant difference in the incidence of male and female in children with KDSS. Children with KDSS compared with non-shocked KD, there were significant difference in age, duration of fever, white blood cell (WBC) count, percentage of neutrophils (NEUT%), platelet count (PLT), c-reactive protein level (CRP), alanine transaminase concentration (ALT), aspartate transaminase concentration (AST), albumin concentration (ALB), sodium concentration (Na), ejection fraction, and length of hospitalization as well as the incidence of coronary artery dilation, coronary artery aneurysm, left ventricular dysfunction, mitral regurgitation, pericardial effusion, initial diagnosis of KD, intravenous immunoglobulin (IVIG) resistance and receiving second dose of IVIG, vasoactive drugs, hormones, and albumin. In contrast, there was no difference in the hemoglobin concentration, erythrocyte sedimentation rate, and the incidence of conjunctival injection, oropharyngeal change, polymorphous rash, extremity change, and incomplete KD.Conclusion: Current evidence suggested that the children with KDSS had more severe indicators of inflammation and more cardiac abnormalities. These patients were resistant to immunoglobulin treatment and required extra anti-inflammatory treatment.Systematic Review Registration: PROSPERO registration number CRD42021241207.
引用
下载
收藏
页数:7
相关论文
共 50 条
  • [41] Dexmedetomidine Withdrawal Syndrome in Children in the PICU: Systematic Review and Meta-Analysis
    Knapp, Thomas
    DiLeonardo, Olivia
    Maul, Tim
    Hochwald, Alexander
    Li, Zhuo
    Hossain, Jobayer
    Lowry, Adam
    Parker, Jason
    Baker, Kimberly
    Wearden, Peter
    Nelson, Jennifer
    PEDIATRIC CRITICAL CARE MEDICINE, 2024, 25 (01) : 62 - 71
  • [42] CLINICAL AND LABORATORY PREDICTORS OF DEATH IN AFRICAN CHILDREN WITH FEATURES OF SEVERE MALARIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
    Sypniewska, Paulina
    Duda, Jose
    Locatelli, Isabella
    Althaus, Clotilde Rambaud
    Althaus, Fabrice
    Genton, Blaise
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 97 (05): : 339 - 339
  • [43] Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis
    Paulina Sypniewska
    Jose F. Duda
    Isabella Locatelli
    Clotilde Rambaud Althaus
    Fabrice Althaus
    Blaise Genton
    BMC Medicine, 15
  • [44] Clinical Features and Outcome of SARS-CoV-2 Infection in Children:A Systematic Review and Meta-analysis
    Meena, Jitendra
    Yadav, Jaivinder
    Saini, Lokesh
    Yadav, Arushi
    Kumar, Jogender
    INDIAN PEDIATRICS, 2020, 57 (09) : 820 - 826
  • [45] COVID-19 infection in children: A systematic review and meta-analysis of clinical features and laboratory findings
    Mansourian, M.
    Ghandi, Y.
    Habibi, D.
    Mehrabi, S.
    ARCHIVES DE PEDIATRIE, 2021, 28 (03): : 242 - 248
  • [46] Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis
    Sypniewska, Paulina
    Duda, Jose F.
    Locatelli, Isabella
    Althaus, Clotilde Rambaud
    Althaus, Fabrice
    Genton, Blaise
    BMC MEDICINE, 2017, 15
  • [47] Clinical features for diagnosis of pneumonia in children younger than 5 years: a systematic review and meta-analysis
    Rambaud-Althaus, Clotilde
    Althaus, Fabrice
    Genton, Blaise
    D'Acremont, Valerie
    LANCET INFECTIOUS DISEASES, 2015, 15 (04): : 439 - 450
  • [48] Clinical Features and Outcome of SARS-CoV-2 Infection in Children: A Systematic Review and Meta-analysis
    Jitendra Meena
    Jaivinder Yadav
    Lokesh Saini
    Arushi Yadav
    Jogender Kumar
    Indian Pediatrics, 2020, 57 : 820 - 826
  • [49] The therapeutic window of intravenous immunoglobulin (IVIG) and its correlation with clinical outcomes in Kawasaki disease: a systematic review and meta-analysis
    Zheng Li
    Jianghui Cai
    Jing Lu
    Mingju Wang
    Chenmei Yang
    Zheng Zeng
    Qian Tang
    Jianhong Li
    Wen Tang
    Huiling Luo
    Gaofeng Pan
    Xingmao Zeng
    Italian Journal of Pediatrics, 49
  • [50] The therapeutic window of intravenous immunoglobulin (IVIG) and its correlation with clinical outcomes in Kawasaki disease: a systematic review and meta-analysis
    Li, Zheng
    Cai, Jianghui
    Lu, Jing
    Wang, Mingju
    Yang, Chenmei
    Zeng, Zheng
    Tang, Qian
    Li, Jianhong
    Tang, Wen
    Luo, Huiling
    Pan, Gaofeng
    Zeng, Xingmao
    ITALIAN JOURNAL OF PEDIATRICS, 2023, 49 (01)