Clinical Features in Children With Kawasaki Disease Shock Syndrome: A Systematic Review and Meta-Analysis

被引:7
|
作者
Zheng, Zhimin [1 ]
Huang, Yanzhi [2 ]
Wang, Zhiyi [1 ]
Tang, Jia [1 ]
Chen, Xiaoqian [1 ]
Li, Ying [1 ]
Li, Meng [1 ]
Zang, Chengye [1 ]
Wang, Yibo [2 ]
Wang, Liwu [2 ]
Ma, Yingwei [2 ]
Sun, Liwei [2 ]
机构
[1] Changchun Univ Chinese Med, Coll Clin Med, Changchun, Peoples R China
[2] Childrens Hosp Changchun, Jilin Childrens Med Ctr, Changchun, Peoples R China
来源
关键词
Kawasaki disease; shock; Kawasaki disease shock syndrome; clinical feature; meta-analysis; LONG-TERM MANAGEMENT; HEALTH-PROFESSIONALS; MANIFESTATIONS; STATEMENT; DIAGNOSIS;
D O I
10.3389/fcvm.2021.736352
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: This study aimed to identify the clinical features of Kawasaki disease shock syndrome (KDSS) in children.Methods: The case-control studies of KDSS and KD children up until April 30, 2021 were searched in multiple databases. The qualified research were retrieved by manually reviewing the references. Review Manager 5.3 software was used for statistical analysis.Results: The results showed that there was no significant difference in the incidence of male and female in children with KDSS. Children with KDSS compared with non-shocked KD, there were significant difference in age, duration of fever, white blood cell (WBC) count, percentage of neutrophils (NEUT%), platelet count (PLT), c-reactive protein level (CRP), alanine transaminase concentration (ALT), aspartate transaminase concentration (AST), albumin concentration (ALB), sodium concentration (Na), ejection fraction, and length of hospitalization as well as the incidence of coronary artery dilation, coronary artery aneurysm, left ventricular dysfunction, mitral regurgitation, pericardial effusion, initial diagnosis of KD, intravenous immunoglobulin (IVIG) resistance and receiving second dose of IVIG, vasoactive drugs, hormones, and albumin. In contrast, there was no difference in the hemoglobin concentration, erythrocyte sedimentation rate, and the incidence of conjunctival injection, oropharyngeal change, polymorphous rash, extremity change, and incomplete KD.Conclusion: Current evidence suggested that the children with KDSS had more severe indicators of inflammation and more cardiac abnormalities. These patients were resistant to immunoglobulin treatment and required extra anti-inflammatory treatment.Systematic Review Registration: PROSPERO registration number CRD42021241207.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] The effectiveness of infliximab for Kawasaki disease in children: systematic review and meta-analysis
    Li, Dan
    Li, Xiaohui
    Dou, Wenting
    Zheng, Yang
    [J]. TRANSLATIONAL PEDIATRICS, 2021, 10 (05) : 1294 - 1306
  • [2] RETRACTED: Comparison of Clinical Features and Inflammatory Markers between Kawasaki Disease Shock Syndrome and Kawasaki Disease without Shock: A Meta-Analysis (Retracted Article)
    Zhang, Hui
    Zheng, Qin
    Li, Feng
    [J]. JOURNAL OF HEALTHCARE ENGINEERING, 2021, 2021
  • [3] Kawasaki Disease and the Use of the Rotavirus Vaccine in Children: A Systematic Review and Meta-Analysis
    Mellone, Natalia Gibim
    Silva, Marcus Tolentino
    Paglia, Mariana Del Grossi
    Lopes, Luciane Cruz
    Barberato-Filho, Silvio
    Del Fiol, Fernando de Sa
    Bergamaschi, Cristiane de Cassia
    [J]. FRONTIERS IN PHARMACOLOGY, 2019, 10
  • [4] Clinical and Laboratory Characteristics of Kawasaki Disease in Iran: A Systematic Review and Meta-analysis
    Bahrami, Masoud
    Ghandi, Yazdan
    [J]. INTERNATIONAL JOURNAL OF PEDIATRICS-MASHHAD, 2020, 8 (12): : 12659 - 12673
  • [5] Clinical Analysis of Kawasaki Disease Shock Syndrome
    Zhang, Ming-Ming
    Shi, Lin
    Li, Xiao-Hui
    Lin, Yao
    Liu, Yang
    [J]. CHINESE MEDICAL JOURNAL, 2017, 130 (23) : 2891 - 2892
  • [6] Clinical Analysis of Kawasaki Disease Shock Syndrome
    Zhang Ming-Ming
    Shi Lin
    Li Xiao-Hui
    Lin Yao
    Liu Yang
    [J]. 中华医学杂志(英文版), 2017, 130 (23) : 2891 - 2892
  • [7] Risk Factors of Coronary Artery Abnormality in Children With Kawasaki Disease: A Systematic Review and Meta-Analysis
    Yan, Fan
    Pan, Bo
    Sun, Huichao
    Tian, Jie
    Li, Mi
    [J]. FRONTIERS IN PEDIATRICS, 2019, 7
  • [8] Systematic review and meta-analysis of the clinical features of MGRS
    Du, Jingxue
    Hu, Zhangxue
    [J]. BMC NEPHROLOGY, 2024, 25 (01)
  • [9] Systematic review and meta-analysis of the clinical features of MGRS
    Jingxue Du
    Zhangxue Hu
    [J]. BMC Nephrology, 25
  • [10] Efficacy of infliximab in the treatment of Kawasaki disease: A systematic review and meta-analysis
    Lu, Zhongxing
    Wang, Fen
    Lv, Haitao
    [J]. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 21 (01)