Microbial dynamics of persistent purulent otitis media in children

被引：30
|
作者：
Brook, I
Frazier, EH
机构：
[1] GEORGETOWN UNIV, SCH MED, DEPT PEDIAT, WASHINGTON, DC 20007 USA
[2] USN HOSP, DEPT INFECT DIS, BETHESDA, MD USA
来源：
JOURNAL OF PEDIATRICS | 1996年 / 128卷 / 02期
关键词：
D O I：
10.1016/S0022-3476(96)70397-9
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Repeated aspirations (for a period of 36 to 55 days) of the exudate through an open perforation were performed in seven children with acute otitis media that did not respond to antimicrobial therapy. Penicillin-resistant organisms were present in all but one of the first two aspirates. Failure to respond to antimicrobial therapy was associated with the emergence of resistant anaerobic and aerobic bacteria in the third and fourth cultures. The infection was cured in all instances after administration of antimicrobial agents effective against these bacteria.
引用
收藏
页码：237 / 240
页数：4
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